Basic information Safety Supplier Related

5-(4-HYDROXYPHENYL)-5-PHENYLHYDANTOIN

Basic information Safety Supplier Related

5-(4-HYDROXYPHENYL)-5-PHENYLHYDANTOIN Basic information

Product Name:
5-(4-HYDROXYPHENYL)-5-PHENYLHYDANTOIN
Synonyms:
  • 2,4-Imidazolidinedione, 5-(4-hydroxyphenyl)-5-phenyl-
  • 2,4-Imidazolidinedione, 5-(4-hydroxyphenyl)-5-phenyl- (9CI)
  • 2,4-Imidazolidinedione, 5-(4-hydroxyphenyl)-5-phenyl-, (.+-.)-
  • 4-Hydroxydiphenylhy
  • (Hydroxyphenyl)phenylhydantoin
  • 5-(para-Hydroxyphenyl)-5-phenylhydantoin
  • (p-hydroxyphenyl)phenylhydantoin
  • 4-hydroxydiphenylhydantoin
CAS:
2784-27-2
MF:
C15H12N2O3
MW:
268.27
EINECS:
220-492-2
Product Categories:
  • Building Blocks
  • Heterocyclic Building Blocks
  • Imidazolines/Imidazolidines
Mol File:
2784-27-2.mol
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5-(4-HYDROXYPHENYL)-5-PHENYLHYDANTOIN Chemical Properties

Melting point:
>300 °C(lit.)
Boiling point:
411.43°C (rough estimate)
Density 
1.1992 (rough estimate)
refractive index 
1.5906 (estimate)
solubility 
soluble50mg/mL, clear, colorless to faintly yellow (DMF:MeOH(2:1))
pka
8.37±0.10(Predicted)
form 
Solid
color 
White to Off-White
Water Solubility 
36mg/L(37 ºC)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
2
RTECS 
MU2485000

MSDS

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5-(4-HYDROXYPHENYL)-5-PHENYLHYDANTOIN Usage And Synthesis

Uses

5-(4-Hydroxyphenyl)-5-phenylhydantoin was used in enantiomeric separation of chiral pharmaceuticals using a teicoplanin chiral stationary phase by aqueous and non-aqueous packed capillary electrochromatography. It was used as internal standard in determination of phenylbutazone and its metabolite oxyphenbutazone in human plasma by GLC.

Definition

ChEBI: A imidazolidine-2,4-dione that consists of hydantoin bearing phenyl and 4-hydroxyphenyl substituents at position 5.

General Description

5-(4-Hydroxyphenyl)-5-phenylhydantoin is the major metabolite of phenytoin.

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