1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE
1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE Basic information
- Product Name:
- 1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE
- Synonyms:
-
- NO-711 HYDROCHLORIDE
- NNC 711
- 1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE
- 1-(2-(((DIPHENYLMETHYLENE)IMINO)OXY)ETHYL)-1,2,5,6-TETRAHYDRO-3-PYRIDINE CARBOXYLIC ACID HYDROCHLORIDE
- NO-711 HCL POTENT GABA UPTAKE IN
- 1,2,5,6-Tetrahydro-1-(2-(((diphenylmethylene)amino)oxy]ethyl)-3-pyridinecarboxylicacidhydrochloride
- NNC711,HCl
- 1-[2-[[(diphenylmethylene)imino]oxy]ethyl]-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid hydrochloride
- CAS:
- 145645-62-1
- MF:
- C21H23ClN2O3
- MW:
- 386.87
- Product Categories:
-
- GABA/Glycine receptor
- Mol File:
- 145645-62-1.mol
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1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE Chemical Properties
- storage temp.
- protect from light
- solubility
- H2O: ≥10 mg/mL at 60 °C
- form
- solid
- color
- off-white
MSDS
- Language:English Provider:SigmaAldrich
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1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE Usage And Synthesis
Uses
NNC 711 is an anticonvulsant agent and a selective GABA uptake inhibitor (1,2).
Uses
NO-711 hydrochloride is suitable for use as γ-aminobutyric acid (GABA) transporter-1 (GAT-1) antagonists or GABA uptake inhibitor.
Biological Activity
Potent and selective inhibitor of GABA uptake by GAT-1 (IC 50 values are 0.04, 171, 1700 and 622 μ M for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). Anticonvulsant following systemic administration in vivo .
Biochem/physiol Actions
NO-711 is a potent and selective GABA uptake inhibitor that crosses the blood-brain barrier.
storage
Desiccate at +4°C
1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDESupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
Sigma-Aldrich
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
EMMX Biotechnology LLC
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- 888-539-0666
- info@emmx.com
TargetMol Chemicals Inc.
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- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
BOC Sciences
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- info@bocsci.com
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1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE(145645-62-1)Related Product Information
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- 1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE
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