5-Fluoroisatonic anhydride
5-Fluoroisatonic anhydride Basic information
- Product Name:
- 5-Fluoroisatonic anhydride
- Synonyms:
-
- 6-FLUORO-2H-3,1-BENZOXAZINE-2,4(1H)-DIONE
- 6-fluoro-1H-benzo[d][1,3]oxazine-2,4-dione
- 6-fluoro-1H-3,1-benzoxazine-2,4-dione
- 6-fluoro-1H-3,1-benzoxazine-2,4-quinone
- 6-FLUORO ISATIN ANHYDRIDE
- 5-FLUOROISATOIC ANHYDRIDE
- 5-FLUOROISATONIC ANHYDRIDE
- 6-Fluorobenzo[d][1,3]oxazine-2,4-dione
- CAS:
- 321-69-7
- MF:
- C8H4FNO3
- MW:
- 181.12
- EINECS:
- 640-488-8
- Product Categories:
-
- Miscellaneous
- Aromatics
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Mol File:
- 321-69-7.mol
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5-Fluoroisatonic anhydride Chemical Properties
- Melting point:
- 259-262°C
- Density
- 1.502±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- soluble in DMSO
- form
- powder
- pka
- 9.61±0.20(Predicted)
- color
- Off-white to pale yellow
- CAS DataBase Reference
- 321-69-7(CAS DataBase Reference)
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5-Fluoroisatonic anhydride Usage And Synthesis
Chemical Properties
Dark yellow Solid
Uses
5-Fluoroisatoic Anhydride is a versatile pharmaceutical intermediate used in the preparation of insulin secretagogues, HCV polymerase inhibitors, anxiolytic agents and other bioactive compounds.
Preparation
5-Fluoroisatonic anhydride is prepared from 5-fluoro indole (9d) by stirring in a 4:1 mixture of DMF/H2O for 16 h at room temperature.
1 H NMR (DMSO-d6): δ11.19 (s, br., 1H), 7.36 (dd, J = 8.4, 2.6 Hz, 1H), 6.87 (dt, J = 8.4, 2.2 Hz, 1H), 6.74 (dd, J = 9.3, 2.2 Hz, 1H).
5-Fluoroisatonic anhydrideSupplier
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Energy Chemical
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5-Fluoroisatonic anhydride(321-69-7)Related Product Information
- Glutaric anhydride
- Phthalic anhydride
- Trifluoromethanesulfonic anhydride
- Succinic anhydride
- 5-Fluoroisatin
- Erythromycin Estolate
- CIS-BUTENEDIOIC ANHYDRIDE
- Chromium(VI) oxide
- Isatoic Anhydride
- Di-tert-butyl dicarbonate
- Indirubin
- Acetic anhydride
- 6-Fluoroisatoic anhydride
- 5-FLUOROISATOIC ANHYDRIDE
- 7-FLUORO-1-H-BENZO[D][1,3]OXAZINE-2,4-DIONE
- 4-FLUOROISATOIC ANHYDRIDE
- 3-FLUOROISATOIC ANHYDRIDE
- 5-Fluoroisatonic anhydride