N-ACETYLPROCAINAMIDE HYDROCHLORIDE Chemical Properties

Melting point:

184-186 °C(lit.)

storage temp. 

−20°C

solubility 

H₂O: 50 mg/mL

form 

powder

color 

Light Beige to Beige

Merck 

13,20

Stability:

Very Hygroscopic

Safety Information

Safety Statements 

24/25

RIDADR 

3249

WGK Germany 

3

HazardClass 

6.1(b)

PackingGroup 

III

HS Code 

29242998

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

N-ACETYLPROCAINAMIDE HYDROCHLORIDE Usage And Synthesis

Description

Acecainide, a main metabolite of procainamide, is a class I a antiarrhythmic agent .

Chemical Properties

yellow-beige crystalline powder

Uses

Cardiac depressant (anti-arrhythmic).

Uses

N-Acetylprocainamide Hydrochloride is an antiarrhythmic agent and a metabolite of Procainamide (P755130). Procainamide is a drug used for both supraventricular and ventricular arrhythmias. For example, it can be used to convert new-onset atrial fibrillation, though it is suboptimal for this purpose. It can also be used to treat Wolff-Parkinson-White syndrome by prolonging the refractory period of the accessory pathway.

General Description

The GLC assay procedure was developed to study the stability of N-acetylprocainamide hydrochloride (acecainide hydrochloride) in rat feed.

Biochem/physiol Actions

Class III antiarrhythmic. Increases the duration of the action potential by decreasing the delayed outward potassium current, slightly decreasing the calcium current, and slightly depressing the inward rectifier potassium current. This is the active metabolite of procainamide that does not induce systemic lupus erythematosus.

N-ACETYLPROCAINAMIDE HYDROCHLORIDE(34118-92-8)Related Product Information

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