DL-Pipecolinic acid
DL-Pipecolinic acid Basic information
- Product Name:
- DL-Pipecolinic acid
- Synonyms:
-
- acidepipecolique
- acidepiperidine-carboxylique-2
- alpha-pipecolinicacid
- dihydrobaikiane
- hexahydropicolinicacid
- pipecolate
- LABOTEST-BB LT00847911
- DL-HOMOPROLINE
- CAS:
- 535-75-1
- MF:
- C6H11NO2
- MW:
- 129.16
- EINECS:
- 208-616-3
- Product Categories:
-
- Piperidine
- Amino Acids & Derivatives
- Heterocycles
- Intermediates
- Amino Acids and Derivatives
- Intermediate
- Mol File:
- 535-75-1.mol
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DL-Pipecolinic acid Chemical Properties
- Melting point:
- 282 °C (dec.)(lit.)
- Boiling point:
- 239.22°C (rough estimate)
- alpha
- [α]D20 -1～+1° (c=2.5, H2O)
- Density
- 1.1426 (rough estimate)
- refractive index
- 1.4587 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Methanol (Slightly), Water (Slightly)
- form
- Fine Crystalline Powder
- pka
- 2.28, 10.72(at 25℃)
- color
- White to light beige
- Water Solubility
- soluble
- Merck
- 14,7458
- BRN
- 81095
- InChIKey
- HXEACLLIILLPRG-UHFFFAOYSA-N
- CAS DataBase Reference
- 535-75-1(CAS DataBase Reference)
- EPA Substance Registry System
- 2-Piperidinecarboxylic acid (535-75-1)
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Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-24/25
- WGK Germany
- 3
- RTECS
- TK6021000
- TSCA
- T
- HazardClass
- IRRITANT
- HS Code
- 29339900
MSDS
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
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DL-Pipecolinic acid Usage And Synthesis
Chemical Properties
white to light beige fine crystalline powder
Uses
Pipecolic acid is involved in synaptic transmission in the central nervous system.
Uses
DL-Pipecolinic acid is used as a diagnostic marker of pyridoxine-dependent epilepsy. It acts as a ligand in copper-catalyzed approach for P-arylation of organophosphorus compounds. It is used as organocatalyst and novel substrate in organic synthesis.
Definition
ChEBI: A piperidinemonocarboxylic acid in which the carboxy group is located at position C-2.
reaction suitability
reaction type: solution phase peptide synthesis
in vivo
Pipecolic acid (intragastric administration; 250 mg/kg; 1 week) can improve diabetic retinopathy in mouse model[2].
| Animal Model: | Male wild-type C57BL/6 mice aged 8 weeks old with Diabetic retinopathy (DR)[3] |
| Dosage: | 250 mg/kg |
| Administration: | Intragastric administration; 1 week |
| Result: | Had positive effects on weight gain and blood sugar level in mice. Significantly reduced the ratio of retinal positive areas to whole positive areas. Regulated oxidative stress and iron metabolism. |
DL-Pipecolinic acid Preparation Products And Raw materials
Preparation Products
DL-Pipecolinic acidSupplier
Anhui Dexinjia Biopharm Co., Ltd Gold
- Tel
- 0531-82375892 15553111391
- 3276840968@qq.com
Sichuan Hainuowei Technology Co. Ltd. Gold
- Tel
- 13708085536 13708085536
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J & K SCIENTIFIC LTD.
- Tel
- 18210857532; 18210857532
- jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel
- 4006356688 18621169109
- market03@meryer.com
INTATRADE GmbH
- Tel
- +49 3493/605464
- sales@intatrade.de
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DL-Pipecolinic acid(535-75-1)Related Product Information
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- DROPERIDOL
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- Hyaluronic acid
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- Quinolinic acid
- Ethyl 2-(Chlorosulfonyl)acetate
- Folic acid
- Haloperidol
- Pyridine-2,6-dicarboxylic acid
- 2-Picolinic acid
- 2,5-PYRIDINEDICARBOXYLIC ACID
- 2,2,6,6-Tetramethyl-4-piperidinol
- Calconcarboxylic acid
- 2-Piperazinecarboxylic acid dihydrochloride
- Citric acid
- 2,6-piperidinedicarboxylic acid