Basic information Safety Supplier Related

8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one

Basic information Safety Supplier Related

8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one Basic information

Product Name:
8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one
Synonyms:
  • 6-chloro-2,9-diazatricyclo[9.4.0.0,3,8]pentadeca-1(15),3,5,7,11,13-hexaen-10-one
  • Clozapine impurity 1/Clozapine EP Impurity A/Clozapine impurity C (USP)/8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one
  • 8-CHLORO-11-OXO-10,11-DIHYDRO-5H-DIBENZO-1,4-DIAZEPINE
  • 8-CHLORO-5,10-DIHYDRO-11H-DIBENZO[B,E][1,4]-DIAZEPIN-11-ONE
  • 8-CHLORO-5,10-DIHYDRODEBENZO[B,E][1,4]DIAZEPIN-11-ONE
  • 8-chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one
  • 8-CHLORO-10,11-DIHYDRO-5H-DIBENZO[B,E][1,4]DIAZEPIN-11-ONE
  • 8-Chloro-11-oxo-10,11-dihydro-5h-debenzo-1,4-diazepine
CAS:
50892-62-1
MF:
C13H9ClN2O
MW:
244.68
Product Categories:
  • (intermediate of clozapine)
  • Aromatics Compounds
  • Aromatics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
50892-62-1.mol
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8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one Chemical Properties

Melting point:
233-236°C
Boiling point:
334.4±41.0 °C(Predicted)
Density 
1.327±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated)
pka
11.68±0.20(Predicted)
form 
Solid
color 
White to Very Dark Grey
Stability:
Store in Freezer
InChI
InChI=1S/C13H9ClN2O/c14-8-5-6-11-12(7-8)16-13(17)9-3-1-2-4-10(9)15-11/h1-7,15H,(H,16,17)
InChIKey
YVWNDABPZGGQFE-UHFFFAOYSA-N
SMILES
N1C(=O)C2=CC=CC=C2NC2=CC=C(Cl)C=C12
CAS DataBase Reference
50892-62-1(CAS DataBase Reference)
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8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one Usage And Synthesis

Chemical Properties

White Solid

Uses

A useful intermediate for the preparation of pharmaceutical actives and fine chemicals. Antipsychotic drug.

Uses

8-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]-diazepin-11-one can be a useful intermediate for the preparation of pharmaceutical actives and fine chemicals.

8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-oneSupplier

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