Basic information Safety Supplier Related

1-METHYLGUANOSINE

Basic information Safety Supplier Related

1-METHYLGUANOSINE Basic information

Product Name:
1-METHYLGUANOSINE
Synonyms:
  • 2-amino-9-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1-methyl-1,9-dihydropurin-6-one
  • 1-Methyl-2-amino-9-(β-D-ribofuranosyl)-9H-purine-6(1H)-one
  • 1-Methyl-2-amino-9-β-D-ribofuranosyl-9H-purine-6(1H)-one
  • Guanosine, 1-methyl- (8ci)(9ci)
  • N1-Methylguanosine
  • Nsc 70897
  • RNA-modified nucleoside m1G
  • 1-METHYLGUANOSINE
CAS:
2140-65-0
MF:
C11H15N5O5
MW:
297.27
Mol File:
2140-65-0.mol
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1-METHYLGUANOSINE Chemical Properties

Melting point:
163 °C
Boiling point:
737.4±70.0 °C(Predicted)
Density 
2.02±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
Methanol (Slightly), Water (Slightly)
pka
13.22±0.70(Predicted)
form 
Solid
color 
White to Off-White
PH
~2.4
λmax
258 (pH 1);256 (pH 6)
Stability:
Hygroscopic
InChI
InChI=1S/C11H15N5O5/c1-15-9(20)5-8(14-11(15)12)16(3-13-5)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14)/t4-,6-,7-,10-/m1/s1
InChIKey
UTAIYTHAJQNQDW-KQYNXXCUSA-N
SMILES
OC[C@H]1O[C@@H](N2C3=C(C(N(C)C(=N3)N)=O)N=C2)[C@H](O)[C@@H]1O
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1-METHYLGUANOSINE Usage And Synthesis

Uses

N1-Methylguanosine-CD3 is the labeled form of N1-Methylguanosine(B426593), which ic use in methods for increasing capping efficiency of transcribed RNA.

Definition

ChEBI: Guanosine substituted with a methyl group at position N-1.

1-METHYLGUANOSINESupplier

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