ADENOSINE-5'-DIPHOSPHOGLUCOSE Chemical Properties

storage temp. 

−20°C

solubility 

PBS (pH 7.2): 10 mg/ml

form 

A crystalline solid

Stability:

Hygroscopic

InChIKey

GKHSIFNCEDGFNS-VKTOLYSKNA-L

SMILES

[Na+].[Na+].C(OP(O[C@H](CO)[C@@H](O)[C@H](O)[C@@H](O)C=O)(OP([O-])([O-])=O)=O)[C@H]1O[C@@H](N2C3=C(C(=NC=N3)N)N=C2)[C@H](O)[C@@H]1O |&1:6,9,11,13,23,25,36,38,r|

Safety Information

WGK Germany 

3

F 

3-10-21

ADENOSINE-5'-DIPHOSPHOGLUCOSE Usage And Synthesis

Description

ADP-Glucose (ADPG) is an immediate precursor used in the biosynthesis, by glucose addition, of storage polysaccharides in plants, green algae, and cyanobacteria, as well as structural polysaccharides in certain bacteria. It is used by amylose synthases or starch synthases in plastids in the production of amylose, amylopectins, starch, and other polysaccharides. ADPG is normally generated within plastids, although it can be biosynthesized in the cytoplasm of certain grasses and imported into plastids by a membrane-bound transporter.

Uses

Adenosine-5′-diphosphoglucose disodium salt has been used as a component of the reaction mixture to measure the enzymatic activity of adenosine-5′-diphosphate (ADP)-glucose pyrophosphorylase (AGPase) and for the synthesis of starch.

Uses

glucose transferase substrate

Biochem/physiol Actions

Adenosine-5′-diphosphoglucose (ADP-Glucose) is a substrate widely used as a glucose donor. It is a substrate starch synthase (EC 2.4.1.21) in starch synthesis. ADP-glucose is a substrate for α-1,4-glucan-protein synthase (ADP-forming) (EC 2.4.1.113), ADP-glucose pyrophosphorylases and many glucosyltransferases.

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