1-[(2R,4S,5S)-4-Amino-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione Chemical Properties

Melting point:

161-1620C

Density 

1.360±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

DMSO (Slightly, Heated), Methanol (Sparingly, Heated)

pka

9.55±0.10(Predicted)

form 

Powder

color 

Off-white to Yellow

Stability:

Hygroscopic and Moisture Sensitive

InChI

InChI=1S/C10H15N3O4/c1-5-3-13(10(16)12-9(5)15)8-2-6(11)7(4-14)17-8/h3,6-8,14H,2,4,11H2,1H3,(H,12,15,16)/t6-,7+,8+/m0/s1

InChIKey

ADVCGXWUUOVPPB-XLPZGREQSA-N

SMILES

OC[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=O)C[C@@H]1N

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

1-[(2R,4S,5S)-4-Amino-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

A metabolite of Zidovudine (3?Azido-3?deoxythymidine; AZT)

1-[(2R,4S,5S)-4-Amino-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione(52450-18-7)Related Product Information

• Fozivudine
• Zidovudine
• 1-[(2R,4S,5S)-4-Amino-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
• 2',3'-Dideoxythymidine
• 3'-Azido-3'-deoxythymidine-5'-triphosphate
• 5'-O-BENZOYL-3'-AZIDO-3'-DEOXYTHYMIDINE
• 3'-AZIDO-3'-DEOXYTHYMIDINE BETA-D-GLUCURONIDE, SODIUM SALT
• 3'-AZIDO-2',3'-DIDEOXY-THYMIDINE-5'-MONOPHOSPHATE, SODIUM SALT
• 3'-AZIDO-3'-DEOXYTHYMIDINE-2-14C
• 5'-PHOSPHONATE-3'-AZIDO-3'-DEOXYTHYMIDINE CALCIUM SALT
• 3'-AZIDO 3'-DEOXYTHYMIDINE, [METHYL-3H]-
• 3'-AZIDO 3'-DEOXYTHYMIDINE 5'-TRIPHOSPHATE, TETRATRIETHYLAMMONIUM SALT, [METHYL-3H]-
• 3'-AZIDO 3'-DEOXYTHYMIDINE 5'-TRIPHOSPHATE, TETRATRIETHYLAMMONIUM SALT
• 3'-AZIDO 3'-DEOXYTHYMIDINE 5'-MONOPHOSPHATE, DIAMMONIUM SALT
• AZT (METHYL-13C)
• 3'-AZIDO 3'-DEOXYTHYMIDINE 5'-MONOPHOSPHATE, DIAMMONIUM SALT, [METHYL-3H]-
• scriptene
• 3'-azido-3'-deoxythymidine 5'-diphosphate