2',3'-Dideoxythymidine Chemical Properties

Melting point:

155-156 °C(lit.)

alpha 

20 º (C=0.6 IN H2O)

Density 

1.332±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,2-8°C

solubility 

DMF: 25 mg/ml,DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml,DMSO: 20 mg/ml

pka

9.55±0.10(Predicted)

form 

Powder

color 

White to Pale Yellow

optical activity

[α]19/D +20.0°, c = 0.6 in H2O

BRN 

21884

InChI

InChI=1S/C10H14N2O4/c1-6-4-12(10(15)11-9(6)14)8-3-2-7(5-13)16-8/h4,7-8,13H,2-3,5H2,1H3,(H,11,14,15)/t7-,8+/m0/s1

InChIKey

XKKCQTLDIPIRQD-JGVFFNPUSA-N

SMILES

O=C1NC(C(=CN1[C@H]1CC[C@H](O1)CO)C)=O

CAS DataBase Reference

3416-05-5(CAS DataBase Reference)

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

F 

10-23

HS Code 

29349990

MSDS

• Language:English Provider:SigmaAldrich

2',3'-Dideoxythymidine Usage And Synthesis

Uses

3’-Deoxythymidine inhibits the ability of bacteriophage T7 to infect Escherichia coli by inhibiting phage DNA synthesis. Also, it is a precursor of DNA polymerase β inhibitor.

Uses

Research tool for antiviral and anticancer studies.

Purification Methods

3'-Deoxyuridine is recrystallised from Me2CO/MeOH and is dried in a vacuum. [Michelson & Todd J Chem Soc 816 1955.]

2',3'-Dideoxythymidine(3416-05-5)Related Product Information

• Thymine
• Floxuridine
• Deoxynucleotide
• Guanosine 5'-monophosphate disodium salt
• Thymidine
• Starch soluble
• Dideoxyadenosine
• 2',3'-Dideoxyguanosine
• 3''-Azido-2'',3''-dideoxythymidine
• DNA, SINGLE STRANDED, IMM. ON CELLULOSE, FROM CALF THYMUS*
• THYMIDINE 5'-TRIPHOSPHATE SODIUM SALT
• 5'-O-Dimethoxytrityl-deoxythymidine
• 5'-O-Tritylthymidine
• Thymidine-5'-monophosphate disodium salt
• Trifluridine
• DMT-dT Phosphoramidite
• 5-Methyluridine
• 3'' -AMINO-2'', 3''-DIDEOXYTHYMIDINE HPLC 98+%,3’-Amino-2’,3’-dideoxythymidine,3''-AMINO-3''-DIDEOXYTHYMIDINE (AMT),3''-AMINO-2'',3''-DIDEOXYTHYMIDINE(AMT)