Adipotide Usage And Synthesis

Description

Adipotide, also known as FTPP or proapoptotic peptide, may potentially eradicate fat cells by specifically targeting the blood supply of those cells. Interestingly, Adipotide is believed to be very selective since it has been hypothesized to differentiate the blood vessels found in fat cells from those found throughout the rest of the organism. Research conducted on monkeys has indicated that Adipotide may reduce weight, increase insulin sensitivity, and mitigate some of the negative consequences of type 2 diabetes. There is a possibility that a protein receptor known as prohibitin may be responsible for mediating the targeting of Adipotide to the blood arteries that supply fat cells. Prohibitin is a membrane protein in cancer cells and blood arteries serving white fat.

Uses

Adipotide as a prototype in a new class of candidate drugs that may be useful for treating obesity in humans.

Physiological effects

Treatment with adipotide induced targeted apoptosis within blood vessels of white adipose tissue and resulted in rapid weight loss and improved insulin resistance in obese monkeys.