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4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide

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4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide Basic information

Product Name:
4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
Synonyms:
  • 2,4-Disulfamyl-5-Trifluoromethylaniline (50 mg)
  • 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide technical, >=96% (HPLC)
  • 1,3-Benzenedisulfonamide, 4-amino-6-(trifluoromethyl)- (9CI)
  • I7C
  • 4-Amino-6-(Trifluoromethyl)Benzene-1,3-Disulphonamide
  • 3-(4-methylphenyl)sulfonylpropane-1,2-diol
  • Bendroflumethiazide EP Impurity A
  • 4-Amino-6-trifluoromethyl-1,3-benzenedisul-famide
CAS:
654-62-6
MF:
C7H8F3N3O4S2
MW:
319.28
EINECS:
211-506-8
Product Categories:
  • A-AM
  • Bioactive Small Molecules
  • Building Blocks
  • Cell Biology
  • Chemical Synthesis
  • Organic Building Blocks
  • Sulfonamides/Sulfinamides
  • Sulfur Compounds
Mol File:
654-62-6.mol
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4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide Chemical Properties

Melting point:
241-246 °C
Boiling point:
562.8±60.0 °C(Predicted)
Density 
1.743±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
9.14±0.60(Predicted)
form 
Solid
color 
White to Off-White
BRN 
1164542
InChI
InChI=1S/C7H8F3N3O4S2/c8-7(9,10)3-1-4(11)6(19(13,16)17)2-5(3)18(12,14)15/h1-2H,11H2,(H2,12,14,15)(H2,13,16,17)
InChIKey
KRVABEGPNKGLOT-UHFFFAOYSA-N
SMILES
C1(S(N)(=O)=O)=C(C(F)(F)F)C=C(N)C(S(N)(=O)=O)=C1
CAS DataBase Reference
654-62-6(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
2935909550

MSDS

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4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide Usage And Synthesis

Chemical Properties

Crystallizes. Melting point 242°C.

Uses

2,4-Disulfamyl-5-trifluoromethylaniline is a carbonic anhydrase inhibitor, used as a potential anti-tumor and antiglaucoma drug. Metabolite of hydroflumethazide, a diuretic.

4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide Preparation Products And Raw materials

Raw materials

4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamideSupplier

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