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N,N'-bis-(2-Chloroethyl)urea

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N,N'-bis-(2-Chloroethyl)urea Basic information

Product Name:
N,N'-bis-(2-Chloroethyl)urea
Synonyms:
  • Carmustine Related Compound A (10 mg) (1,3-bis(2-chloroethyl)urea)
  • CarMustine Related CoMpound A
  • BCU
  • NSC 36198
  • 3-(diethylamino)-1-(2,4,6-trimethoxyphenyl)-1-propanone
  • Carmustine impurity A CRS
  • Carmustine impurity A (C0580010)
  • Urea, N,N'-bis(2-chloroethyl)-
CAS:
2214-72-4
MF:
C5H10Cl2N2O
MW:
185.05
Product Categories:
  • Mutagenesis Research Chemicals
Mol File:
2214-72-4.mol
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N,N'-bis-(2-Chloroethyl)urea Chemical Properties

Melting point:
128-129 °C
Boiling point:
358.2±27.0 °C(Predicted)
Density 
1.245±0.06 g/cm3(Predicted)
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
12.99±0.46(Predicted)
Stability:
Hygroscopic, Unstable in Solution
InChIKey
VBWBRZHAGLZNST-UHFFFAOYSA-N
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Safety Information

HS Code 
2924190002
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N,N'-bis-(2-Chloroethyl)urea Usage And Synthesis

Uses

1,3-Bis(2-chloroethyl)urea is an impurity in the synthesis of Carmustine (C183875), an alkylating and carbamoylating nitrosourea compound. It interacts with DNA, RNA and proteins causing DNA interstrand cross linking which is cytotoxic and leads to apoptotic cell death.

N,N'-bis-(2-Chloroethyl)urea Preparation Products And Raw materials

Raw materials

N,N'-bis-(2-Chloroethyl)ureaSupplier

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