Basic information Safety Supplier Related

Alclometasone

Basic information Safety Supplier Related

Alclometasone Basic information

Product Name:
Alclometasone
Synonyms:
  • ALCLOMETHASONE DIPROPIONATE
  • 7α-Chloro-16α-methylprednisolone
  • 7α-Chloro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione
  • Alclometasone
  • Vaderm
  • (7α,11β,16α)-7-Chloro-11,17,21-trihydroxy-16-Methylpregna-1,4-diene-3,20-dione
  • AlcloMethasone
  • Pregna-1,4-diene-3,20-dione, 7-chloro-11,17,21-trihydroxy-16-methyl-, (7α,11β,16α)-
CAS:
67452-97-5
MF:
C22H29ClO5
MW:
408.919
Product Categories:
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Steroids
Mol File:
67452-97-5.mol
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Alclometasone Chemical Properties

Melting point:
176-179°
alpha 
D26 +47.5° (c = 0.3 in DMF)
Boiling point:
607.1±55.0 °C(Predicted)
Density 
1.34±0.1 g/cm3(Predicted)
pka
12.30±0.70(Predicted)
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Alclometasone Usage And Synthesis

Uses

A metabolite of Alclometasone dipropionate (A514580); a synthetic glucocorticoid steroid for topical use in dermatology as anti-inflammatory, antipruritic, antiallergic, antiproliferative and vasoconstrictive agent.

Uses

As a metabolite of Alclometasone dipropionate; Alclometasone can be used as a synthetic glucocorticoid steroid for topical use in dermatology as anti-inflammatory, antipruritic, antiallergic, antiproliferative and vasoconstrictive agent.

Definition

ChEBI: A prednisolone compound having an alpha-chloro substituent at the 7-position and an alpha-methyl substituent at the 16-position.

brand name

Aclovate (GlaxoSmithKline).

AlclometasoneSupplier

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