Mometasone
Mometasone Basic information
- Product Name:
- Mometasone
- Synonyms:
-
- icariins
- Mometasone (Mometasone Furoate EP Impurity G)
- MOMETASONE
- 9a,21-dichloro-11b,17-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione
- MometasoneFuroateBase
- Mometasone Furoate EP Impurity G/Mometasone
- Pregna-1,4-diene-3,20-dione, 9,21-dichloro-11,17-dihydroxy-16-methyl-, (11.beta.,16.alpha.)-
- Pregna-1,4-diene-3,20-dione, 9,21-dichloro-11,17-dihydroxy-16-methyl-, (11b,16a)- (9CI)
- CAS:
- 105102-22-5
- MF:
- C22H28Cl2O4
- MW:
- 427.36
- EINECS:
- 818-819-4
- Mol File:
- 105102-22-5.mol
Mometasone Chemical Properties
- Melting point:
- >211oC (dec.)
- Boiling point:
- 586.6±50.0 °C(Predicted)
- Density
- 1.35±0.1 g/cm3(Predicted)
- storage temp.
- Refrigerator, Under Inert Atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
- pka
- 12.08±0.70(Predicted)
- form
- Solid
- color
- White to Pale Beige
- InChIKey
- WOFMFGQZHJDGCX-MCUOXHNDNA-N
- SMILES
- [C@]1(OC(=O)C2OC=CC=2)([C@H](C)C[C@@]2([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]12C)C(CCl)=O |&1:0,9,12,14,24,26,28,31,r|
- CAS DataBase Reference
- 105102-22-5(CAS DataBase Reference)
Mometasone Usage And Synthesis
Chemical Properties
Pale Yellow Solid
Uses
Mometasone (Mometasone EP Impurity G) is a potent topical corticosteroid. Mometasone has potent antiinflammatory activity and is used in the treatment of dermatological disorders. It can be applied to the skin, inhaled, or used in the nose. It is used to alleviate inflammation and itchiness in skin conditions that respond to treatment with glucocorticoids such as psoriasis and atopic dermatitis. Mometasone furoate, not mometasone, is used in medical products.
Definition
ChEBI: Mometasone is an 11beta-hydroxy steroid, a 17alpha-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid, a chlorinated steroid and a tertiary alpha-hydroxy ketone. It has a role as an anti-inflammatory drug, a dermatologic drug, a vasoconstrictor agent and an anti-allergic agent. It is functionally related to a Delta(1)-progesterone.
Side effects
The most common side effects are an unpleasant smell and a dry or sore nose or throat.
MometasoneSupplier
- Tel
- 400-6009262 16621234537
- chenyj@titansci.com
- Tel
- 1-(800)-881-8210
- inquiries@lgmpharma.com
- Tel
- 021-50135380
- shchemsky@sina.com
- Tel
- info@syntechem.com
- Tel
- 1-631-485-4226; 16314854226
- info@bocsci.com
Mometasone(105102-22-5)Related Product Information
- Betamethasone 21-phosphate disodium
- Betamethasone 17-valerate
- Dichloroacetic acid
- N,N-Dimethylallylamine
- 6-Methyl-5-hepten-2-one
- Mesityl oxide
- Betamethasone
- 3-Chloro-2-methylpropene
- 2-Chloro-3-hydroxypyridine
- 21-CHLORO-9,11-EPOXY-17-HYDROXY-16-METHYL-1,4-
- Allyl methacrylate
- Solvent Red 43
- METHYLCYCLOPENTADIENE DIMER
- MOMETASONE FUROATE,MOMETASONE 17-FUROATE,MOMETASONE FUAROATE,Mometasone 17-(2-furoate)
- MOMETASONE FUROATE-D3
- Mometasone
- fluocortolone/mometasone/clocortolone
- Mometasone furoate USP