1-hydrazino-3-(methylthio)propan-2-ol Chemical Properties

Boiling point:

128-130 °C(Press: 1 Torr)

Density 

1.145±0.06 g/cm3(Predicted)

pka

13.98±0.20(Predicted)

1-hydrazino-3-(methylthio)propan-2-ol Usage And Synthesis

Chemical Properties

White powder

Uses

1-hydrazino-3-(methylthio)propan-2-ol, also known as 3-methylmercapto-2-hydroxy-propyl hydrazine, is an important organic reagent that can be used as a building block for the synthesis of many organic compounds. It can be used to synthesize N-amino-5-methylmercapto-methyl-2-oxazolidinone which is an intermediate of nifuratel.

Synthesis

Add 226.25g hydrazine hydrate to 1000ml reaction flask, heat to 90℃, and add 104.17g of glycidyl ether under stirring. The temperature of the reaction system was controlled at 90℃, and then the excess hydrazine hydrate was concentrated under reduced pressure to obtain 120.10g thick colorless liquid. The purity of the gas phase was 96.8%, namely 1-hydrazino-3-(methylthio)propan-2-ol, and the yield was 88.30%.

1-hydrazino-3-(methylthio)propan-2-ol (14359-97-8)Related Product Information

• 3-amino-5-[(methylthio)methyl]oxazolidin-2-one
• Nifuratel Impurity 4
• Nifuratel Impurity 4
• 2,5-Dihydro-2-hydroxy-5-nitro-2-furanMethanediol Triacetate
• Hydrazine sulfate
• 2-Furancarboxaldehyde, 3-nitro- (9CI)
• 2-Furoic acid
• 3-METHYLTHIO-1,2-PROPANEDIOL
• nifurprazine
• Nifuratel Impurity 20 (Mixture of Diastereomers)
• 1,3-BIS(METHYLTHIO)-2-PROPANOL
• QUISQUALIC ACID
• 5-Nitro-2-furaldehyde diacetate
• 5-nitro-2-furaldehyde (5-nitrofurfurylene)hydrazone
• 1-METHYLTHIO-2,3-EPOXYPROPANE
• 5-Nitrofurfural
• Nifuratel Impurity
• Nifuratel