ChemicalBook > Product Catalog > Pharmaceutical intermediates > Heterocyclic compound > Pyran compounds > Centchroman
Centchroman
Centchroman Basic information
- Product Name:
- Centchroman
- Synonyms:
-
- Centchroman
- 1-[2-[p-(trans-7-Methoxy-2,2-diMethyl-3-phenyl- 4-chroManyl)phenoxy]ethyl]pyrrolidine
- 3,4-trans-2,2-DiMethyl-3-phenyl-4-[p-(β- py
- rel-1-[2-[4-[(3R,4R)-3,4-dihydro-7-Methoxy-2,2-diMethyl-3-phenyl-2H-1-benzopyran-4-yl]phenoxy]ethyl]pyrrolidine
- Pyrrolidine, 1-[2-[4-[(3R,4R)-3,4-dihydro-7-methoxy-2,2-dimethyl-3-phenyl-2H-1-benzopyran-4-yl]phenoxy]ethyl]-, rel-
- Centchroman ISO 9001：2015 REACH
- CAS:
- 31477-60-8
- MF:
- C30H35NO3
- MW:
- 457.6
- EINECS:
- 256-846-9
- Product Categories:
-
- Aromatics
- Chiral Reagents
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Mol File:
- 31477-60-8.mol
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Centchroman Chemical Properties
- Melting point:
- 99-101°
- Boiling point:
- 563.39°C (rough estimate)
- Density
- 1.1065 (rough estimate)
- refractive index
- 1.6310 (estimate)
- storage temp.
- 2-8°C
- solubility
- Soluble in DMSO
- pka
- 9.61±0.20(Predicted)
- form
- oil
- color
- colorless to light brown
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Centchroman Usage And Synthesis
Description
Centchroman is a new, weekly, orally active contraceptive with weak estrogenic and potent antiestrogenic properties.It is reported to be the first non-hormonal, non-steroidal oral contraceptive. Centchroman acts by inhibiting the implantation of fertilized eggs in the uterus. With the exception of longer menstrual cycles, no side effects have been reported. Another indication under study is the treatment of hormone dependent breast cancer.
Originator
Central Drug Research Institute (India)
Uses
Centchroman is an estrogen antagonist. Centchroman is a synthetic nonsteroidal postcoital antifertility agent.
brand name
Choice-7
CentchromanSupplier
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
LGM Pharma
- Tel
- 1-(800)-881-8210
- inquiries@lgmpharma.com
Chemsky (shanghai) International Co.,Ltd
- Tel
- 021-50135380
- shchemsky@sina.com
TaiChem Taizhou Limited
- Tel
- 052386810091
- zcwy9518@yeah.net
JinJin Le Chemical Co., Ltd
- Tel
- 10106090
- jjlchem2@163.com