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tert-Butyl 2-(aminomethyl)phenylcarbamate

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tert-Butyl 2-(aminomethyl)phenylcarbamate Basic information

Product Name:
tert-Butyl 2-(aminomethyl)phenylcarbamate
Synonyms:
  • 2-(Aminomethyl)aniline, 1-BOC protected
  • 2-[(tert-Butoxycarbonyl)amino]benzylamine, tert-Butyl [2-(aminomethyl)phenyl]carbamate
  • tert-Butyl N-[2-(aminomethyl)phenyl]carbamate
  • 2-(tert-Butoxycarbonylamino)benzylamine
  • 2-(Boc-amino)benzylamine
  • 2-(Aminomethyl)-N-Boc-aniline
  • TERT-BUTYL 2-(AMINOMETHYL)PHENYLCARBAMATE
  • ert-Butyl N-(2-aminomethylphenyl)carbamate
CAS:
849020-94-6
MF:
C12H18N2O2
MW:
222.28
Product Categories:
  • Building Blocks
  • Chemical Synthesis
  • Nitrogen Compounds
  • Organic Building Blocks
  • Polyamines
  • Protected Amines
Mol File:
849020-94-6.mol
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tert-Butyl 2-(aminomethyl)phenylcarbamate Chemical Properties

Boiling point:
238-242℃
Density 
1.054g/mLat 25℃
Flash point:
71°C
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
13.67±0.70(Predicted)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22-43
Safety Statements 
36/37
RIDADR 
NA 1993 / PGIII
WGK Germany 
3
HS Code 
2921490090
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tert-Butyl 2-(aminomethyl)phenylcarbamate Usage And Synthesis

Uses

Reactant for:

  • Two-step syntheses of fused quinoxaline-benzodiazepines and bis-benzodiazepines employing a double UDC (Ugi/Deprotect/Cyclize) strategy
  • Preparation of hydroquinazoline scaffolds via microwave-promoted Ugi reaction and cyclization
  • Preparation of pyrazinone inhibitors of mast cell tryptase

Uses

Tert-Butyl 2-(aminomethyl)phenylcarbamate can be used as reactant for Two-step syntheses of fused quinoxaline-benzodiazepines and bis-benzodiazepines employing a double UDC (Ugi/Deprotect/Cyclize)

tert-Butyl 2-(aminomethyl)phenylcarbamateSupplier

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