Flutrimazole
Flutrimazole Basic information
- Product Name:
- Flutrimazole
- Synonyms:
-
- flutrimazole:1-((2-fluorophenyl)-(4-fluorophenyl)phenylmethyl)-1h-IMIDAZOLE
- 1-[(2-Fluorophenyl)(4-fluorophenyl)(phenyl)methyl]imidazole
- 1-((2-fluorophenyl)(4-fluorophenyl)phenylmethyl)-1h-imidazol
- 1-(o-fluoro-alpha-(p-fluorophenyl)-alpha-phenylbenzyl)imidazole
- flutrimazol
- 1-[(2-fluorophenyl)-(4-fluorophenyl)phenylmethyl]-1h-imidazole
- FLUTRIMAZOLE
- FLUTRIMAZOLC
- CAS:
- 119006-77-8
- MF:
- C22H16F2N2
- MW:
- 346.37
- Product Categories:
-
- Flutrimazole
- API
- Mol File:
- 119006-77-8.mol
Flutrimazole Chemical Properties
- Melting point:
- 161-166℃
- Boiling point:
- 457.1±40.0 °C(Predicted)
- Density
- 1.15±0.1 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- Practically insoluble in water, freely soluble in tetrahydrofuran, soluble in methanol.
- pka
- 6.03±0.34(Predicted)
- form
- Solid
- color
- White to Pale Yellow
- CAS DataBase Reference
- 119006-77-8(CAS DataBase Reference)
Flutrimazole Usage And Synthesis
Description
Flutrimazole, a novel imidazole antifungal launched in Spain, is indicated for mycosis of the skin. Flutrimazole displays potent broad-spectrum of activity against dematophytes, filamentous fungi and yeasts, saprophytic and pathogenic to animals and humans. Similar to other imidazole and triazole antifungals, flutrimazole exerts its biological function through inhibition of fungal lanosterol 14a-demethylase. Excellent local and systemic tolerance of flutrimazole in patients has been reported.
Chemical Properties
White or almost white powder.
Originator
Uriach (Spain)
Uses
Flutrimazole is a new imidazole antifungal agent with anti-inflammatory properties as well.
Definition
ChEBI: An imidazole antifungal agent that is imidazole in which the hydrogen attached to the nitrogen is replaced by a 2,4'-difluorotrityl group. A topical antifungal agent which displays potent broad-spectrum in vitro activity against dermatophytes, filamentous fungi and yeasts.
brand name
Micetal
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