16-Hydroxytriptolide CAS#: 139713-80-7

16-Hydroxytriptolide Basic information

Product Name:

16-Hydroxytriptolide

Synonyms:

16-Hydroxytriptolide
Trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-6a-[(1S)-2-hydroxy-1-methylethyl]-, (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-
Triheptanoin Impurity 7

CAS:

139713-80-7

MF:

C20H24O7

MW:

376.4

Mol File:

139713-80-7.mol

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16-Hydroxytriptolide Chemical Properties

Melting point:: 232-233.5 °C
Boiling point:: 659.7±55.0 °C(Predicted)
Density: 1.56±0.1 g/cm3(Predicted)
pka: 14.16±0.60(Predicted)

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16-Hydroxytriptolide Usage And Synthesis

Uses

16-Hydroxytriptolide is a diterpenoid triepoxide naturally isolated from Tripterygium wilfordii plant. This compound showed definite antiinflammatory action, strong immunosuppressive and antifertility activities.

Definition

ChEBI: 16-hydroxytriptolide is a tetracyclic diterpenoid with formula C20H24O7, originally isolated from the roots and leaves of Tripterygium wilfordii. It has a role as a plant metabolite, a rat metabolite and a xenobiotic metabolite. It is a gamma-lactone, an epoxide, a secondary alcohol, a tetracyclic diterpenoid, a primary alcohol and a diol.

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