1'-Hydroxybufuralol CAS#: 57704-16-2

1'-Hydroxybufuralol Basic information

Product Name:

1'-Hydroxybufuralol

Synonyms:

Ro 03-7410
2-(tert-Butylamino)-1-[7-(1-hydroxyethyl)-1-benzofuran-2-yl]ethanol
1’-Hydroxy Bufuralol (Mixture of Diastereomers)
1'-Hydroxybufuralol
α2-[[(1,1-DiMethylethyl)aMino]Methyl]-α7-Methyl-
2-(tert- Butylamino)-1-(7-(1- hydroxyethyl)benzofuran-2- yl)ethanol maleate
Bufuralol Impurity 3(Mixture of Diastereomers)
Bufuralol Impurity 3-d9(Mixture of Diastereomers)

CAS:

57704-16-2

MF:

C16H23NO3

MW:

277.36

Product Categories:

Aromatics
Heterocycles
Metabolites & Impurities

Mol File:

57704-16-2.mol

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1'-Hydroxybufuralol Chemical Properties

Melting point:: 41-49°C
Boiling point:: 433.0±40.0 °C(Predicted)
Density: 1.139±0.06 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
form: Solid
pka: 13.58±0.20(Predicted)
color: Off-White to Beige
Stability:: Hygroscopic

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1'-Hydroxybufuralol Usage And Synthesis

Description

1’-hydroxy Bufuralol is a metabolite of bufuralol . Bufuralol is metabolized by the cytochrome P450 isoforms 2D1 and 2D2 (CYP2D1/2); therefore, quantification of the bufuralol metabolite, 1’-hydroxy bufuralol, can be used to determine CYP2D1/2 enzyme activity in humans and rats.

Chemical Properties

White to Off-White Solid

Uses

A metabolite of Bufuralol, a β-Adrenergic blocker with peripheral vasodilating activity.

1'-HydroxybufuralolSupplier

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