4-Methylphenylsulfonylurea Chemical Properties

Melting point:

196-198 °C

Density 

1.3844 (rough estimate)

refractive index 

1.5690 (estimate)

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

5.07±0.10(Predicted)

form 

Solid

color 

White to Off-White

Water Solubility 

777.9mg/L(37 ºC)

InChI

InChI=1S/C8H10N2O3S/c1-6-2-4-7(5-3-6)14(12,13)10-8(9)11/h2-5H,1H3,(H3,9,10,11)

InChIKey

RUTYWCZSEBLPAK-UHFFFAOYSA-N

SMILES

C1(S(NC(N)=O)(=O)=O)=CC=C(C)C=C1

CAS DataBase Reference

1694-06-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

45-36/37/39-26

HS Code 

2935.90.9500

MSDS

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4-Methylphenylsulfonylurea Usage And Synthesis

Chemical Properties

white crystalline powder

Uses

N-(p-Toluenesulfonyl)urea is used in the synthesis of Glyburide (G598350), a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic agent.

Uses

4-Methylphenylsulfonylurea can be used as pharmaceutical intermediate.

Uses

4-Methylphenylsulfonylurea is used in the synthesis of Glyburide (G598350), a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic agent.

4-Methylphenylsulfonylurea(1694-06-0)Related Product Information

• Tosyl cyanide
• 4-Methylbenzenesulfonhydrazide
• Tosylmethyl isocyanide
• Tosyl chloride
• Toluenesulfonamide
• 4-Hydroxytolbutamide
• Tosyl azide
• TOLBUTAMIDE
• p-Toluenesulfonamide
• Glibenclamide
• TOLAZAMIDE
• Glipizide
• ACETOHEXAMIDE
• Gliclazide
• Tolpentamide
• 4-Methylphenylsulfonylurea
• 4-Carboxytolbutamide Methyl Ester
• 4-(4-METHYLPHENYLSULFONYL)SEMICARBAZIDE HYDROCHLORIDE