Basic information Safety Supplier Related

4-Methylphenylsulfonylurea

Basic information Safety Supplier Related

4-Methylphenylsulfonylurea Basic information

Product Name:
4-Methylphenylsulfonylurea
Synonyms:
  • 4-tolylsulfonylurea
  • N-(p-Toluenesulfonyl)urea
  • BenzenesulfonaMide,N-(aMinocarbonyl)-4-Methyl-
  • 4-TOLUENSULFONYLUREA
  • Para-Toluene Sulfonyl Urea
  • Tolbutamide EP Impurity B
  • Gliclazide Impurity 12
  • N-(Aminocarbonyl)-4-methylbenzensulfona-mide
CAS:
1694-06-0
MF:
C8H10N2O3S
MW:
214.24
EINECS:
216-900-3
Product Categories:
  • chemical additive
  • pharmaceutical intermediate
Mol File:
1694-06-0.mol
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4-Methylphenylsulfonylurea Chemical Properties

Melting point:
196-198 °C
Density 
1.3844 (rough estimate)
refractive index 
1.5690 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
5.07±0.10(Predicted)
form 
Solid
color 
White to Off-White
Water Solubility 
777.9mg/L(37 ºC)
CAS DataBase Reference
1694-06-0(CAS DataBase Reference)
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Safety Information

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
45-36/37/39-26
HS Code 
2935.90.9500

MSDS

  • Language:English Provider:ACROS
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4-Methylphenylsulfonylurea Usage And Synthesis

Chemical Properties

white crystalline powder

Uses

N-(p-Toluenesulfonyl)urea is used in the synthesis of Glyburide (G598350), a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic agent.

Uses

4-Methylphenylsulfonylurea can be used as pharmaceutical intermediate.

Uses

4-Methylphenylsulfonylurea is used in the synthesis of Glyburide (G598350), a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic agent.

4-Methylphenylsulfonylurea Preparation Products And Raw materials

Raw materials

4-MethylphenylsulfonylureaSupplier

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