4-Methylbenzenesulfonhydrazide Chemical Properties

Melting point:

103-108 °C(lit.)

Boiling point:

340.5±35.0 °C(Predicted)

Density 

1.42g/cm3

vapor pressure 

0Pa at 20℃

refractive index 

1.5400 (estimate)

Flash point:

60°C

storage temp. 

Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

solubility 

5g/l

pka

9.39±0.10(Predicted)

form 

Powder

color 

White or off-white to slightly grayish

Water Solubility 

5 g/L (15 ºC)

Sensitive 

Moisture Sensitive

BRN 

610130

Stability:

Light Sensitive

InChIKey

ICGLPKIVTVWCFT-UHFFFAOYSA-N

LogP

0.55 at 25℃

CAS DataBase Reference

1576-35-8(CAS DataBase Reference)

EPA Substance Registry System

Benzenesulfonic acid, 4-methyl-, hydrazide (1576-35-8)

Safety Information

Hazard Codes 

F,Xn

Risk Statements 

11-22-44-2017/11/22

Safety Statements 

16-26

RIDADR 

UN 3226 4.1

WGK Germany 

3

RTECS 

MW0210000

TSCA 

Yes

HazardClass 

4.1

PackingGroup 

II

HS Code 

29280090

MSDS

• Language:English Provider:p-Toluenesulfonhydrazide
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-Methylbenzenesulfonhydrazide Usage And Synthesis

Uses

p-Toluenesulfonyl Hydrazide is a reactant that has been used in the synthesis of paspaline.

Chemical Properties

white to off-white powder

Uses

p-Toluenesulfonyl hydrazide is used as a reagent for the preparation of tosylhydrazones. It was used to prepare dipyrazolo[1,5-a:4?,3?-c]pyridines and 1,2,3-selenadiazole derivatives.

Uses

4-Methylbenzenesulfonhydrazide was widely used reagent for the preparation of tosylhydrazones.

Flammability and Explosibility

Not classified

Purification Methods

Dissolve the hydrazide in hot MeOH (~1g/4mL), filter through Celite and precipitate the material by adding 2-2.5 volumes of distilled H2O. Dry it in air or in a vacuum. [Fiedman et al. Org Synth Coll Vol V 1055 1973, Beilstein 11 II 66.]

4-Methylbenzenesulfonhydrazide(1576-35-8)Related Product Information

• p-Toluenesulfonyl semicarbazide
• Tosylmethyl isocyanide
• Toluenesulfonamide
• p-Anisaldehyde
• 4-Methoxyphenol
• 4-Methylphenylsulfonylurea
• p-Anisidine
• Tosyl azide
• 4-Nitrobenzonitrile
• 4-Methoxybenzyl cyanide
• p-Toluenesulfonamide
• p-Toluidine
• Tosyl chloride
• Maleic hydrazide
• antioxidant 1024
• 1-[1-(Bromomethyl)ethenyl]-2,4-difluoro-benzene
• PHENYL {4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE
• 2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one,