Basic information Safety Supplier Related

4-MALEIMIDO-TEMPO

Basic information Safety Supplier Related

4-MALEIMIDO-TEMPO Basic information

Product Name:
4-MALEIMIDO-TEMPO
Synonyms:
  • 4-maleimido-2,2,6,6-tetramethylpiperidinooxyl
  • 4-MALEIMIDO-TEMPO
  • 4-MALEIMIDO-TEMPO, FREE RADICAL
  • 4-MALEIMIDO-2,2,6,6-TETRAMETHYL-1-PIPERIDINYLOXY
  • N-(1-Oxyl-2,2,6,6-tetramethyl-4-piperidinyl)maleinimide
  • TEMPO-Maleimide, 4-Maleimido-TEMPO, MAL 6,
  • 4-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-2,2,6,6-tetramethyl-1-piperidinyloxy
  • 4-maleimido-2,2,6,6-tetramethyl-1-piperidinyloxy, free radical
CAS:
15178-63-9
MF:
C13H19N2O3*
MW:
251.3
Product Categories:
  • Maleimide Derivatives
  • Spin Labeling Compounds
  • Heterocycles
  • MTS & Sulfhydryl Active Reagents
Mol File:
15178-63-9.mol
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4-MALEIMIDO-TEMPO Chemical Properties

Melting point:
91-94 °C
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
color 
Orange to Dark Orange
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
24/25-36-26
WGK Germany 
3

MSDS

  • Language:English Provider:ACROS
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4-MALEIMIDO-TEMPO Usage And Synthesis

Chemical Properties

Red-Orange Solid

Uses

A thiol specific spin label.

Uses

4-Maleimido-TEMPO (4-Maleimido-2,2,6,6,-tetramethylpiperidinooxyl) was employed as spin label to investigate the influence of bile salts on the intact rat mitochondrial membranes by electron paramagnetic resonance spectroscopy (EPR). It may be employed as spin label for the labeling of erythrocyte membranes to investigate the interaction of quercetin with erythrocyte proteins by EPR spectra.

Definition

ChEBI: 4-maleimido-TEMPO is a member of the class of piperidines that is TEMPO carrying a maleimido group at position 4. It has a role as a radical scavenger and a spin label. It is a member of aminoxyls, a member of piperidines, a member of maleimides and a dicarboximide. It is functionally related to a TEMPO.

General Description

4-Maleimido-TEMPO, a water-soluble nitroxide radical, is commonly employed as spin probe. It has been reported to inhibit the survival of CHO cells at 1mM concentrations. It is widely employed maleimide spin label for EPR studies.

Biochem/physiol Actions

Spin label used to study fluidity of brain synaptosomal membranes, internal microviscosity of erythrocytes, and human high density lipoproteins.

4-MALEIMIDO-TEMPOSupplier

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