BIS(4-HYDROXYCINNAMOYL)METHANE
BIS(4-HYDROXYCINNAMOYL)METHANE Basic information
- Product Name:
- BIS(4-HYDROXYCINNAMOYL)METHANE
- Synonyms:
-
- BIS-DESMETHOXYCURCUMIN
- BIS(4-HYDROXYCINNAMOYL)METHANE
- DEMETHOXYCURCUMIN, BIS-
- CURCUMIN 3
- (1E,6E)-1,7-bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione
- BIS-(PARA-HYDROXYCINNAMOYL)METHANE
- CURCUMINIII
- 1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione
- CAS:
- 24939-16-0
- MF:
- C19H16O4
- MW:
- 308.33
- EINECS:
- 607-464-9
- Product Categories:
-
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Mol File:
- 24939-16-0.mol
BIS(4-HYDROXYCINNAMOYL)METHANE Chemical Properties
- Melting point:
- 91-93℃
- Boiling point:
- 551.3±45.0 °C(Predicted)
- Density
- 1.285
- storage temp.
- 2-8°C
- solubility
- DMSO: ≥20mg/mL
- pka
- 8.67±0.46(Predicted)
- form
- Solid
- color
- Light yellow to Brown
- Stability:
- Light Sensitive
- InChIKey
- PREBVFJICNPEKM-YDWXAUTNSA-N
- LogP
- 3.155 (est)
BIS(4-HYDROXYCINNAMOYL)METHANE Usage And Synthesis
Chemical Properties
Yellow powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from turmeric rhizomes, turmeric, and zedoary turmeric.
Uses
Bisdemethoxycurcumin is one of the three major forms of curcuminoids found in the rhizomes of turmeric. Bisdemethoxycurcumin displays antioxidant, anti-inflammatory as well as chemotherapeutic activity. Bisdemethoxycurcumin acts as an inhibitor of human pancreatic a-amylase, a target for type-2 diabetes .
Definition
ChEBI: Bisdemethoxycurcumin is a beta-diketone that is methane in which two of the hydrogens are substituted by 4-hydroxycinnamoyl groups. It has a role as a metabolite and an EC 3.2.1.1 (alpha-amylase) inhibitor. It is a beta-diketone, a polyphenol, an enone and a diarylheptanoid. It is functionally related to a 4-coumaric acid.
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