ChemicalBook > Product Catalog > Biochemical Engineering > Amino Acids and Derivatives > Glutamic acid derivatives > N-CARBAMYL-L-GLUTAMIC ACID
N-CARBAMYL-L-GLUTAMIC ACID
N-CARBAMYL-L-GLUTAMIC ACID Basic information
- Product Name:
- N-CARBAMYL-L-GLUTAMIC ACID
- Synonyms:
-
- N-CARBAMYL-L-GLUTAMIC ACID
- carbamino-l-glutamicacid
- carbamylglutamicacid
- NCG,N-carbamyl-L-glutamic acid
- N-(Aminocarbonyl)-L-Glutamic Acid(Carglumic Acid)
- N-Carbamyl-L-glutamate
- N-Cbm-Glu-OH
- N-Carbamyl-L-glutamic
- CAS:
- 1188-38-1
- MF:
- C6H10N2O5
- MW:
- 190.15
- EINECS:
- 601-569-3
- Product Categories:
-
- CARBAGLU
- A - H
- Amino Acids
- Modified Amino Acids
- Mol File:
- 1188-38-1.mol
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N-CARBAMYL-L-GLUTAMIC ACID Chemical Properties
- Melting point:
- 174°
- Boiling point:
- 438.1±45.0 °C(Predicted)
- Density
- 1.499±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- DMSO (Slightly), Methanol (Slightly, Sonicated)
- form
- Solid
- pka
- 3.71±0.10(Predicted)
- color
- White to Off-White
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MSDS
- Language:English Provider:SigmaAldrich
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N-CARBAMYL-L-GLUTAMIC ACID Usage And Synthesis
Uses
carbamylphosphate synthetase activator
Uses
N-Carbamyl-L-glutamic Acid has been shown to have protective effects against ammonia intoxication and is used in the treatment of acute hyperammonemia.
Definition
ChEBI: A urea that is the N-carbamoyl derivative of L-glutamic acid. An orphan drug used to treat a deficiency in the enzyme N-acetylglutamate synthase, which leads to acute hyperammonaemia.
Biological Activity
N-Carbamyl-L-glutamic acid (carglumic acid) is use to study its potential as a replacement therapy for N-acetylglutamate synthetase (NAGS) deficiency and to tre at hyperammonemia.
N-CARBAMYL-L-GLUTAMIC ACIDSupplier
Hubei Hicks Biochemical Co., Ltd Gold
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- 17362916295; 17362916295
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JIURUI BIOLOGY & CHEMISTRY CO.,LTD. Gold
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- 0744-8561603 18507445225
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J & K SCIENTIFIC LTD.
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- 010-82848833 400-666-7788
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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- 021-61259108 18621169109
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BeiJing Hwrk Chemicals Limted
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- 0757-86329057 18934348241
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