Propargyl butylcarbamate Chemical Properties

Boiling point:

233°C

Density 

0.990

vapor pressure 

0.41-76Pa at -1.51-50℃

refractive index 

1.452

Flash point:

95°C

storage temp. 

2-8°C

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Oil

pka

12.03±0.46(Predicted)

color 

Clear Colourless

Odor

Mild odor

LogP

1.86-1.9 at 25℃ and pH7.2

Surface tension

55.47mN/m at 1g/L and 20℃

EPA Substance Registry System

Carbamic acid, butyl-, 2-propynyl ester (76114-73-3)

Propargyl butylcarbamate Usage And Synthesis

Uses

Used in the preparation of cosmetic and pharamceutical products.

General Description

Propargyl Butylcarbamate is a chemical compound known for its role as a biocide and stabilizer. It finds various applications across different industries due to its unique properties.

Synthesis

The general procedure for the synthesis of 2-alkynyl-N-butylcarbamates from butyl bromide and 2-propyn-1-ol is as follows: Example I Synthesis of benzyl propargyl carbamate: a mixture of n-butyl bromide (8.8 g, 0.064 mol), 2-propyn-1-ol (3 g, 0.054 mol), potassium cyanide (6.5 g, 0.08 mol), and tetrabutylammonium bromide (1.7 g, 0.005 mol) was heated to 70 °C in acetonitrile (45 mL), and the reaction was carried out under nitrogen protection for 22 hours. After completion of the reaction, the insoluble precipitate was removed by filtration and the filtrate was concentrated by rotary evaporator to give a yellow oil (6.7 g). Purification by column chromatography (silica gel, 15/85 ethyl acetate/hexane) gave N-alkynyl carbamate (4.4 g, 53% yield) as a colorless oil. NMR (CDCl3, ppm): δ 4.75 (2H, s), 3.2 (2H, m), 2.5 (1H, s), 1.4 (4H, m), 1.0 (3H, t). GC/MS (m/e): 155 (M+), 112 (100%), 74, 57, 56.

References

[1] Patent: EP539092, 1993, A1

Propargyl butylcarbamate(76114-73-3)Related Product Information

• tert-Butanol
• Lithium diisopropylamide
• butyl rubber
• 3-Chloropropyne
• Methyl anthranilate
• Methyl 4-tert-butylbenzoate
• Chlorpropham
• POLYURETHANE
• Butyl acetate
• Buprofezin
• Cyhalofop-butyl
• 2-Butoxyethanol
• Urethane
• 4-Aminobenzoic acid
• Butyl acrylate
• Propargyl bromide
• ISOCYANATE
• Propargyl alcohol