Basic information Safety Supplier Related

-N7-DGTP

Basic information Safety Supplier Related

-N7-DGTP Basic information

Product Name:
-N7-DGTP
Synonyms:
  • 7-DEAZA-2'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE LITHIUM SALT
  • 7-DEAZA-2'-DEOXYGUANOSINE-5'-TRIPHOSPHORIC ACID, LITHIUM
  • 7-DEAZA-DGTP, LI
  • 7-DEAZA-DGTP LITHIUM SALT
  • -N7-DGTP
  • 7-deaza-2'-deoxyguanosine 5'-*triphosphate lithiu
  • 7-DEAZA-2'-DEOXYGUANOSINE 5'-*TRIPHOSPHA TE LITHIUM
  • 2'-deoxy-7-deazaguanosine triphosphate
CAS:
101515-08-6
MF:
C11H17N4O13P3
MW:
506.19
Product Categories:
  • Pharmaceutical
  • Nucleotide
Mol File:
101515-08-6.mol
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-N7-DGTP Chemical Properties

Density 
2.48±0.1 g/cm3(Predicted)
storage temp. 
-20°C
pka
0.97±0.50(Predicted)
form 
solution
color 
colorless
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Safety Information

WGK Germany 
3

MSDS

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-N7-DGTP Usage And Synthesis

Uses

7-Deaza-dGTP is a substrate for most DNA polymerases, including Taq DNA polymerase.
7-Deaza-dGTP is used in the dideoxy-chain termination sequencing methods, in place of dGTP to overcome compression problems in gel electrophoresis when sequencing GC-rich stretches of DNA.
Partial substitution of 7-Deaza-dGTP for dGTP in PCRs can improve the product yield when the template is GC-rich (i.e., has extensive secondary structures).

General Description

7-Deaza-2′-deoxyguanosine 5′-triphosphate enhances polymerase chain reaction (PCR) product yield.

Biochem/physiol Actions

This dGTP analog pairs weakly with conventional bases to minimize DNA secondary structures, while being a good substrate for DNA ploymerases.

-N7-DGTPSupplier

BOC Sciences Gold
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Olive Biotech(Tianjin)CO.,Ltd. Gold
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Sigma-Aldrich
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Alfa Chemistry
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