4,7-Dichloro-1,10-phenanthroline Chemical Properties

Melting point:

243-247 °C

Boiling point:

395.9±37.0 °C(Predicted)

Density 

1.482±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

pka

3.29±0.10(Predicted)

form 

solid

color 

white to tan

InChI

InChI=1S/C12H6Cl2N2/c13-9-3-5-15-11-7(9)1-2-8-10(14)4-6-16-12(8)11/h1-6H

InChIKey

GIEQBYJCGYHHSU-UHFFFAOYSA-N

SMILES

N1C2C(=CC=C3C=2N=CC=C3Cl)C(Cl)=CC=1

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-37/38-41

Safety Statements 

26-39

RIDADR 

UN 2811 6.1/PG 3

WGK Germany 

3

TSCA 

No

HazardClass 

6.1

HS Code 

29339900

Storage Class

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications

Acute Tox. 3 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3

4,7-Dichloro-1,10-phenanthroline Usage And Synthesis

Application

1,10-phenanthroline can be used as an intermediate in fluorescent materials, mainly in the fields of life sciences and medicine, catalysis, and novel optoelectronic materials.

Synthesis

Take 4.16g (10mmol) of 1,2-bis-[(2,2-dimethyl-4,6-dioxo-1,3-dioxane-5-ylidenemethyl)amino]benzene in 300mL of p-phenylene ether reflux for 30min, the mixture was cooled down to room temperature, when added to cyclohexane there was a large amount of precipitate precipitation precipitation, filtration and washed out of the p-phenylene ether with cyclohexane, vacuum drying to obtain 32.43g of light yellow powder crude The product was dried under vacuum to give 32.43g of light yellow powder crude product with a yield of about 99%. This product does not need to be purified, and can be directly carried out the next step of the reaction. Take 2.1g (10mmol) 4,7-dioxo-1,10-o-phenanthroline, add to 60g (210mmo1) phosphorus trichloride, under the protection of nitrogen reaction for 30min, the reaction solution was poured into 400mL of ice-water mixture, adjusted to pH 7-8 with 10% NaOH, extracted with dichloromethane (100mLx3), the organic layer was combined, dried with anhydrous magnesium sulfate, rotary evaporation with column chromatography. Drying, rotary evaporation and column chromatography gave 1.74 g of white powder product 4,7-dichloro-1,10-phenanthroline in 70% yield.

4,7-Dichloro-1,10-phenanthroline(5394-23-0)Related Product Information

• 1,10-Phenanthroline hydrate
• 4,7-DIMETHOXY-1,10-PHENANTHROLINE, 97%
• Potassium chromate
• 1,10-Phenanthroline, 4,7-dibroMo-
• 1,10-Phenanthroline-5-carboxylic acid
• o-Phenanthroline monohydrochloride monohydrate
• 4,7-DIHYDROXY-1,10-PHENANTHROLINE
• Bathophenanthroline
• o-Phenanthroline
• 2,9-Dichloro-1,10-phenanthroline
• 3,8-Dibromophenanthroline
• 2，9-dibromo-1,10-phenanthroline
• 5,6-diamino-1,10-phenanthroline
• 1 10-PHENANTHROLINE-5 6-DIONE 97
• 1,10-PHENANTHROLINE-2,9-DICARBOXYLIC ACID
• 4,7-Dimethyl-1,10-phenanthroline