Ambazone hydrate Chemical Properties

Melting point:

188 °C (decomp)(Solv: water (7732-18-5); ammonia (7664-41-7))

Ambazone hydrate Usage And Synthesis

Originator

Ambazone,Generic

Manufacturing Process

To a solution of 22.7 g of quinone monoguanylhydrazone nitrate in 250 ml water is added dropwise hot aqueous solution of 9.1 g thiosemicarbazide, then is added slowly a solution of 5 ml concentrated nitric acid in 10 ml of water. The mixture is stirred at 60°C for 1 hour. The product is dissolved in 1-1.2 L of water at 100°C. The solution is filtered and added to an aqueous ammonium solution. Blue residue of p-benzoquinone amidinohydrazone thiosemicarbazone is filtered and dried, melting point 188°C (decomp.).

Therapeutic Function

Antiseptic

Ambazone hydrate(6011-12-7)Related Product Information

• Ambazone