Ambazone Chemical Properties

Melting point:

195°C (rough estimate)

Boiling point:

160°C (rough estimate)

Density 

1.2732 (rough estimate)

refractive index 

1.5500 (estimate)

storage temp. 

Hygroscopic, Refrigerator, under inert atmosphere

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

color 

Red to Very Dark Brown

Stability:

Very Hygroscopic

EPA Substance Registry System

Hydrazinecarbothioamide, 2-[4-[(aminoiminomethyl)hydrazono]-2,5-cyclohexadien-1-ylidene]- (539-21-9)

Ambazone Usage And Synthesis

Originator

Ambazone,Generic

Uses

Ambazone is a benzoquidine diimine derivative useful as animal growth substance.

Definition

ChEBI: Ambazone is a hydrazone.

Manufacturing Process

To a solution of 22.7 g of quinone monoguanylhydrazone nitrate in 250 ml water is added dropwise hot aqueous solution of 9.1 g thiosemicarbazide, then is added slowly a solution of 5 ml concentrated nitric acid in 10 ml of water. The mixture is stirred at 60°C for 1 hour. The product is dissolved in 1-1.2 L of water at 100°C. The solution is filtered and added to an aqueous ammonium solution. Blue residue of p-benzoquinone amidinohydrazone thiosemicarbazone is filtered and dried, melting point 188°C (decomp.).

Therapeutic Function

Antiseptic

Ambazone(539-21-9)Related Product Information

• N,N'-Diethylthiourea
• N-Aminothiourea
• 2-Cyclohexen-1-one
• Difurazone
• 2-(2-Aminoethyl)isothiourea dihydrobromide
• Cyclohexanone
• Bis(cyclohexanone)oxaldihydrazone
• Cyclohexene
• Hydrazodicarbothioamide
• PHENYL VALERATE
• Dithizone
• 1-PHENYL-2-THIOUREA
• Phenylacetic acid
• 1,4-HEXADIENE
• Ambazone hydrate
• [4-(amidinohydrazono)cyclohexa-2,5-dienal] semicarbazone
• Ambazone Impurity
• 3-(4-oxocyclohexa-2,5-dien-1-ylidene)carbazamidine