VINYL CHLOROFORMATE Chemical Properties

Boiling point:

68-69 °C735 mm Hg(lit.)

Density 

1.166 g/mL at 20 °C(lit.)

vapor pressure 

0.88 psi ( 20 °C)

refractive index 

n20/D 1.41(lit.)

Flash point:

24 °F

storage temp. 

2-8°C

form 

Liquid

color 

Clear colorless

BRN 

1741679

Safety Information

Hazard Codes 

F,T

Risk Statements 

23/24/25-34-11

Safety Statements 

16-26-36-45-36/37

RIDADR 

UN 3390 6.1/PG 1

WGK Germany 

3

F 

10-21-19

HazardClass 

6.1(a)

PackingGroup 

II

HS Code 

29159000

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

VINYL CHLOROFORMATE Usage And Synthesis

Chemical Properties

clear colourless liquid

Uses

Vinyl Chloroformate was used to prepare analogues of the Nicotinic Acetylcholine Receptor Agonist (±)-UB-165. It was also used to synthesize possible antitumor agents such as paclitaxel-2''-carbonates and N-carbamyl triazenes.

Purification Methods

It has been fractionated through a Todd column (p 11, Model A with ~60 plates) under atmospheric pressure and the purity can be checked by gas chromatography. Stabilize it with 0.5% of 2,6-di-tert-butyl-p-cresol. It has IR with at 3100 + 2870 (CH2), 1780 (C=O), 1640 (C=C) and 940 (CH2out-of-plane) and 910 (CH2 wagging) cm-1. [IR: Lee J Org Chem 30 3943 1965, Levaillant Ann Chim (Paris) 6 504 1936.] It is used for protecting NH2 groups in peptide synthesis [Olofson et al. Tetrahedron Lett 1563 1977]. [Beilstein 3 III 28.]

VINYL CHLOROFORMATE(5130-24-5)Related Product Information

• VINYL PROPIONATE
• VINYL NEONONANOATE
• VINYL FORMATE
• Isopropenyl chloroformate
• Chloromethyl methyl ether
• Methyl chloroformate
• Methoxyethene
• VINYL CHLOROFORMATE