rac-Febrifugine Dihydrochloride
rac-Febrifugine Dihydrochloride Basic information
- Product Name:
- rac-Febrifugine Dihydrochloride
- Synonyms:
-
- rac-Febrifugine Dihydrochloride
- 3-[3-[(2R,3S)-3-Hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone dihydrochloride
- Febrifugine dihydrochloride
- Atensil
- ISF-2123
- Pildralazine dihydrochloride
- Propyldazine hydrochloride
- Inhibitor,Parasite,Febrifugine dihydrochloride,antimalarial,alkaloid,Quinazolinone,inhibit,Febrifugine
- CAS:
- 32434-42-7
- MF:
- C16H19N3O3
- MW:
- 301.34036
- Product Categories:
-
- Aromatics, Intermediates
- Mol File:
- 32434-42-7.mol
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rac-Febrifugine Dihydrochloride Chemical Properties
- Melting point:
- 220-222 °C (decomp)
- storage temp.
- -20°C
- solubility
- H2O: soluble15mg/mL, clear
- form
- powder
- color
- off-white to gray to brown
- optical activity
- [α]/D 10 to 15°, c = 1 in H2O
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rac-Febrifugine Dihydrochloride Usage And Synthesis
Chemical Properties
White Solid
Uses
rac-Febrifugine dihydrochloride is the salt of Febrifugine, a bioactive constituent of a Chinese medicinal herb that is characterized by its therapeutic activity regarding malaria, cancer, fibrosis and inflammatory diseases.
Biochem/physiol Actions
Febrifugine dihydrochloride exhibits strong antimalarial activity against Plasmodium falciparum, the most insidious malaria causative agent. The adverse effects of febrifugine include diarrhoea, vomiting and liver toxicity.
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