rac-Febrifugine Dihydrochloride
rac-Febrifugine Dihydrochloride Basic information
- Product Name:
- rac-Febrifugine Dihydrochloride
- Synonyms:
-
- rac-Febrifugine Dihydrochloride
- 3-[3-[(2R,3S)-3-Hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone dihydrochloride
- Febrifugine dihydrochloride
- Atensil
- ISF-2123
- Pildralazine dihydrochloride
- Propyldazine hydrochloride
- Inhibitor,Parasite,Febrifugine dihydrochloride,antimalarial,alkaloid,Quinazolinone,inhibit,Febrifugine
- CAS:
- 32434-42-7
- MF:
- C16H19N3O3
- MW:
- 301.34036
- Product Categories:
-
- Aromatics, Intermediates
- Mol File:
- 32434-42-7.mol
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rac-Febrifugine Dihydrochloride Chemical Properties
- Melting point:
- 220-222 °C (decomp)
- storage temp.
- -20°C
- solubility
- H2O: soluble15mg/mL, clear
- form
- powder
- color
- off-white to gray to brown
- optical activity
- [α]/D 10 to 15°, c = 1 in H2O
- Water Solubility
- H2O: 15mg/mL, clear
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rac-Febrifugine Dihydrochloride Usage And Synthesis
Chemical Properties
White Solid
Uses
rac-Febrifugine dihydrochloride is the salt of Febrifugine, a bioactive constituent of a Chinese medicinal herb that is characterized by its therapeutic activity regarding malaria, cancer, fibrosis and inflammatory diseases.
Biochem/physiol Actions
Febrifugine dihydrochloride exhibits strong antimalarial activity against Plasmodium falciparum, the most insidious malaria causative agent. The adverse effects of febrifugine include diarrhoea, vomiting and liver toxicity.
IC 50
Plasmodium
rac-Febrifugine DihydrochlorideSupplier
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