3,4-Dichlorophenylacetonitrile Chemical Properties

Melting point:

39-42 °C (lit.)

Boiling point:

170 °C/12 mmHg (lit.)

Density 

1.4274 (rough estimate)

refractive index 

1.5690 (estimate)

Flash point:

>230 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Crystalline Powder

color 

White

BRN 

638749

Exposure limits

NIOSH: IDLH 25 mg/m3

Stability:

Light Sensitive

CAS DataBase Reference

3218-49-3(CAS DataBase Reference)

NIST Chemistry Reference

3,4-Dichlorophenylacetonitrile(3218-49-3)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

20/21/22-36/37/38

Safety Statements 

26-37/39-36/37/39

RIDADR 

3276

WGK Germany 

3

Hazard Note 

Irritant

HazardClass 

6.1

PackingGroup 

III

HS Code 

29269095

MSDS

• Language:English Provider:3,4-Dichlorophenylacetonitrile
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

3,4-Dichlorophenylacetonitrile Usage And Synthesis

Chemical Properties

WHITE CRYSTALLINE POWDER

Uses

3,4-Dichlorophenylacetonitrile was used in the synthesis of:

• SR 48968, a potent, competitive and selective non-peptide antagonist of the neurokinin A (NK2) receptor
• tachykinin NK3 receptor antagonist SR 142801, (R)-N-[ 1-[3-[ 1-benzoyl-3-(3,4-dichlororphenyl)-3-piperidinyl]propyyl]-4-phenyl-4-piperidinyl-N-methyl acetamide
• MDL 105,212, a non-peptide tachykinin receptor antagonist

3,4-Dichlorophenylacetonitrile(3218-49-3)Related Product Information

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