SUC-ALA-ALA-PRO-ARG-PNA Chemical Properties

Density 

1.50±0.1 g/cm3(Predicted)

storage temp. 

-15°C

pka

4.69±0.10(Predicted)

Sequence

{Suc-Ala}-Ala-Pro-{Arg-pNA}

SUC-ALA-ALA-PRO-ARG-PNA Usage And Synthesis

Uses

Suc-AAPR-pNA is a substrate of trypsin acyl-enzymes. Suc-AAPR-pNA can be used to test trypsin acyl-enzymes activity[1][2].

References

[1] DeSantis G, et, al. Toward tailoring the specificity of the S1 pocket of subtilisin B. lentus: chemical modification of mutant enzymes as a strategy for removing specificity limitations. Biochemistry. 1999 Oct 5;38(40):13391-7. DOI:10.1021/bi990861o
[2] Radisky ES, et, al. Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates. Proc Natl Acad Sci U S A. 2006 May 2;103(18):6835-40. DOI:10.1073/pnas.0601910103

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