Basic information Description References Safety Supplier Related
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L-Cyclohexylalanine

Basic information Description References Safety Supplier Related

L-Cyclohexylalanine Basic information

Product Name:
L-Cyclohexylalanine
Synonyms:
  • (S)-CYCLOHEXYLALANINE
  • 3-CYCLOHEXYL-L-ALANINE HYDROCHLORIDE
  • 3-CYCLOHEXYL-L-ALANINE HYDROCHLORIDE SALT
  • 3-CYCLOHEXYL-L-ALANINE
  • H-CHA-OH
  • H-CHA-OH HCL
  • H-BETA-CYCLOHEXYL-ALA-OH HCL
  • HEXAHYDRO-L-PHENYLALANINE HCL
CAS:
27527-05-5
MF:
C9H17NO2
MW:
171.24
EINECS:
1308068-626-2
Product Categories:
  • chiral
Mol File:
27527-05-5.mol
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L-Cyclohexylalanine Chemical Properties

Melting point:
322 °C
Boiling point:
307.1±25.0 °C(Predicted)
Density 
1.075±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
pka
2.33±0.10(Predicted)
form 
Solid
CAS DataBase Reference
27527-05-5(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-37/39-26
WGK Germany 
3
10
Hazard Note 
Irritant
HS Code 
2922498590
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L-Cyclohexylalanine Usage And Synthesis

Description

L-Cyclohexylalanine is a kind of amino acid analog. It has some pharmacological effects. Study has shown that some of its derivatives exhibit potent bactericidal activity against drug-resistant gram-positive pathogens. Its derivatives can also act as dipeptidyl peptidase-IV inhibitor, which can be used for the treatment or prevention of diabetes. 

References

http://nizetlab.ucsd.edu/Publications/CombinatorialLibrary.pdf
Duffy, Joseph L, et al. "Cyclohexylalanine derivatives as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes." CN, CN 1960990 A. 2007.
Aarstad, K, T. L. Zimmer, and S. G. Laland. "The fidelity of gramicidin S synthetase." European Journal of Biochemistry 112.2(1980):335-338.

Chemical Properties

white to light yellow crystal powder

Uses

(S)-(+)-Cyclohexylalanine

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