Basic information Safety Supplier Related

2',6-DIHYDROXYFLAVONE

Basic information Safety Supplier Related

2',6-DIHYDROXYFLAVONE Basic information

Product Name:
2',6-DIHYDROXYFLAVONE
Synonyms:
  • 6-hydroxy-2-(2-hydroxyphenyl)-4H-1-benzopyran-4-one, DHF
  • 2',6-DIHYDROXYFLAVONE
  • 4H-1-Benzopyran-4-one, 6-hydroxy-2-(2-hydroxyphenyl)-
  • 6-hydroxy-2-(2-hydroxyphenyl)chromen-4-one
  • 6,2'Dihydroxyflavone,Gamma-aminobutyric acid Receptor,γ-Aminobutyric acid Receptor,6,2'-Dihydroxyflavone,GABA Receptor,Inhibitor,inhibit,6,2' Dihydroxyflavone
  • 6,2'-Dihydroxyflavone
  • 6,2''-Dihydroxyflavone
  • 6,2''-Dihydroxyflavone, 10 mM in DMSO
CAS:
92439-20-8
MF:
C15H10O4
MW:
254.24
Product Categories:
  • Di-substituted Flavones
Mol File:
92439-20-8.mol
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2',6-DIHYDROXYFLAVONE Chemical Properties

storage temp. 
Room temp
solubility 
DMSO : 155 mg/mL (609.66 mM)
form 
Solid
color 
Light yellow to yellow
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Safety Information

Hazard Codes 
T
Risk Statements 
25-36
Safety Statements 
26-45
RIDADR 
UN 2811 6.1/PG 3
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2',6-DIHYDROXYFLAVONE Usage And Synthesis

Uses

6,2''-Dihydroxyflavone, is a novel GABAA receptor antagonist.

in vivo

6,2'-Dihydroxyflavone-treated mice exhibit significant differences from control mice with respect to the percentage of open arms entries [F(4,73)=8.01, P<0.0001] and the percentage of time spent in open arms [F (4,73)=5.19, P<0.002], but not the number of entries to closed arms [F(4,73)= 0.79,P=0.54]. The post-hoc NewmaneKeuls’ tests confirm that 6,2'-Dihydroxyflavone significantly decreases the percentage of open arm entries and time spent in open arms at the doses of 8 and 16 mg/kg. 6,2'-Dihydroxyflavone treatment similarly increases step-through latency [F(4,75)=4.71, P<0.002], suggesting enhanced cognitive performance[1].

2',6-DIHYDROXYFLAVONESupplier

Alfa Aesar
Tel
400-6106006
Email
saleschina@alfa-asia.com
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Email
3007715519@qq.com
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Shanghai Tombiopharma Chemical Co. Ltd.
Tel
13391076197
Email
tombiopharma@163.com
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Email
3008007409@qq.com