Basic information Safety Supplier Related

N-SUCCINIMIDYL 6-(3-MALEIMIDOPROPIONAMIDO) HEXANOATE

Basic information Safety Supplier Related

N-SUCCINIMIDYL 6-(3-MALEIMIDOPROPIONAMIDO) HEXANOATE Basic information

Product Name:
N-SUCCINIMIDYL 6-(3-MALEIMIDOPROPIONAMIDO) HEXANOATE
Synonyms:
  • 6-(3-Maleimidopropionylamino)-hexanoic acid-NHS ester
  • 6-[[3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]aMino]hexanoic Acid 2,5-Dioxo-1-pyrrolidinyl Ester
  • SMPH Crosslinker
  • N-[6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-2,5-dihydro-2,5-dioxo-1H-pyrrole-1-propanamide
  • N-SUCCINIMIDYL 6-(3-MALEIMIDOPROPIONAMIDO) HEXANOATE
  • 6-(N-[3-MALEIMIDOPROPIONAMIDO])HEXANOATE-SUCCINIMIDE
  • SMPH (Succinimidyl 6-((beta-maleimidopropionamido)hexanoate))
  • Hexanoic acid, 6-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]-, 2,5-dioxo-1-pyrrolidinyl ester
CAS:
367927-39-7
MF:
C17H21N3O7
MW:
379.36
Product Categories:
  • Maleimide Derivatives
  • Cross Linking Reagents
  • MTS & Sulfhydryl Active Reagents
Mol File:
367927-39-7.mol
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N-SUCCINIMIDYL 6-(3-MALEIMIDOPROPIONAMIDO) HEXANOATE Chemical Properties

storage temp. 
2-8°C
solubility 
DMSO or DMF: soluble
form 
powder
InChI
1S/C17H21N3O7/c21-12(9-11-19-13(22)5-6-14(19)23)18-10-3-1-2-4-17(26)27-20-15(24)7-8-16(20)25/h5-6H,1-4,7-11H2,(H,18,21)
InChIKey
WCMOHMXWOOBVMZ-UHFFFAOYSA-N
SMILES
O=C(CCCCCNC(CCN1C(C=CC1=O)=O)=O)ON2C(CCC2=O)=O
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Safety Information

WGK Germany 
WGK 3
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
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N-SUCCINIMIDYL 6-(3-MALEIMIDOPROPIONAMIDO) HEXANOATE Usage And Synthesis

Description

SMPH Crosslinker is a non-cleavable, water soluble crosslinker containing a maleimide and NHS ester group. The maleimide is able to react with thiol groups between pH 6.5 to 7.5 to form thiolester bonds. NHS ester groups are reactive toward primary amines.

Chemical Properties

17.7

Uses

A sulfhydryl and amino reactive heterobifunctional crosslinking reagent. Spacer Arm: 14.3 Angstroms

Uses

carbonyl and sulfhydryl reactive heterobifunctional cross-linking reagent

Uses

A sulfhydryl and amino reactive heterobifunctional crosslinking reagent.Spacer Arm: 14.3 Angstroms

reaction suitability

reagent type: cross-linking reagent

IC 50

Alkyl/ether

N-SUCCINIMIDYL 6-(3-MALEIMIDOPROPIONAMIDO) HEXANOATESupplier

J & K SCIENTIFIC LTD.
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