Basic information Safety Supplier Related

N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate

Basic information Safety Supplier Related

N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate Basic information

Product Name:
N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate
Synonyms:
  • N-Succinimidyl 4-(maleimidomethyl)cyclohexanecarboxylate, SMCC
  • SMCC [4-(N-Maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester]
  • trans-4-(Maleimidomethyl)-cyclohexane carboxylic acid-NHS ester
  • N-SucciniMidyl 4-(N-MaleiMidoMethyl)cyclohexanecarboxylate
  • 4-(N-MaleiMidoMethyl)cyclohexane-1-carboxylic acid N-hydroxysucciniMide ester, 98+%
  • NSC 344483
  • 4-(N-Maleimidomethyl)cyclohexanecarboxylic Acid N-Succinimidyl Ester SMCC
  • 25MG/100MG/10G
CAS:
64987-85-5
MF:
C16H18N2O6
MW:
334.32
EINECS:
1592732-453-0
Product Categories:
  • heteroXlink
  • Heterobifunctional Crosslinker
  • Maleimide Derivatives
  • Cross Linking Reagents
  • MTS & Sulfhydryl Active Reagents
Mol File:
64987-85-5.mol
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N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate Chemical Properties

Melting point:
180-182 °C (lit.)
Boiling point:
501.7±42.0 °C(Predicted)
Density 
1.42±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
chloroform: 50 mg/mL
pka
-2.24±0.20(Predicted)
form 
powder
Sensitive 
Moisture & Light Sensitive
BRN 
1555271
CAS DataBase Reference
64987-85-5(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-60-37
WGK Germany 
3
10-21
HS Code 
29280000

MSDS

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N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate Usage And Synthesis

Chemical Properties

White Crystalline Solid

Uses

A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. It conjugates anti-digoxin F(ab’)2 fragments to ?-galactosidase. Conjugates hIgG to alkaline phosphatase. Spacer Arm: 11.6 Angstroms

Definition

ChEBI: An N-hydroxysuccinimide ester derived from 4-(N-maleimidomethyl)cyclohexane-1-carboxylic acid.

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