N-Succinimidyl 3-maleimidopropionate
N-Succinimidyl 3-maleimidopropionate Basic information
- Product Name:
- N-Succinimidyl 3-maleimidopropionate
- Synonyms:
-
- N-(3-MALEIMIDOPROPIONYLOXY)SUCCINIMIDE
- N-MALEOYL-BETA-ALANINE N'-HYDROXYSUCCINIMIDE ESTER
- N-SUCCINIMIDYL 3-MALEIMIDOPROPIONATE
- 3-MALEIMIDOPROPIONIC ACID N-HYDROXYSUCCINIMIDE ESTER
- 3-MALEIMIDOPROPIONIC ACID N-SUCCINIMIDYL ESTER
- MALEIMIDOPROPIONIC ACID N-HYDROXYSUCCINIMIDE ESTER
- 3-Maleidopropionic acid N-hydroxysuccynimide ester (SMP)
- B-MALEIMIDOPROPIONIC ACID N-*HYDROXYSUCCINIMIDE ESTE
- CAS:
- 55750-62-4
- MF:
- C11H10N2O6
- MW:
- 266.21
- EINECS:
- 627-755-4
- Product Categories:
-
- Building Blocks
- Carbonyl Compounds
- Maleimide Derivatives
- N-Substituted Maleimides
- Chemical Biology
- Chemical Synthesis
- N-Substituted Maleimides, Succinimides & Phthalimides
- N-Substituted Succinimides
- Cross Linking Reagents
- MTS & Sulfhydryl Active Reagents
- Crosslinkers
- Cyclic Imides
- Heterobifunctional Crosslinker
- heteroXlink
- Linkers and Crosslinkers
- Organic Building Blocks
- Mol File:
- 55750-62-4.mol
N-Succinimidyl 3-maleimidopropionate Chemical Properties
- Melting point:
- 168-170 °C(lit.)
- Boiling point:
- 448.8±47.0 °C(Predicted)
- Density
- 1.55±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- -2.39±0.20(Predicted)
- color
- White to Light Brown
- Water Solubility
- Insoluble in water.
- Sensitive
- Moisture Sensitive
- BRN
- 1492578
- InChI
- InChI=1S/C11H10N2O6/c14-7-1-2-8(15)12(7)6-5-11(18)19-13-9(16)3-4-10(13)17/h1-2H,3-6H2
- InChIKey
- JKHVDAUOODACDU-UHFFFAOYSA-N
- SMILES
- N1(CCC(ON2C(=O)CCC2=O)=O)C(=O)C=CC1=O
- CAS DataBase Reference
- 55750-62-4(CAS DataBase Reference)
Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 37
- Safety Statements
- 26-36/37/39-24/25
- WGK Germany
- 3
- F
- 10-21
- HS Code
- 29280000
MSDS
- Language:English Provider:SigmaAldrich
N-Succinimidyl 3-maleimidopropionate Usage And Synthesis
Description
3-Maleimido-propionic NHS ester contains a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
Chemical Properties
White to off-white solid
Uses
3-Maleimidopropionic acid N-hydroxysuccinimide ester is a reagent that is widely used for generating stable maleimide-activated carrier proteins that can spontaneously react with sulfhydryls. Alternatively these relatively stable maleimide-activated intermediates may be lyophilized and stored for later conjugation to a hapten.
Uses
A short, sulfhydryl and amino reactive heterobifunctional crosslinking reagent, N-Succinimidyl 3-maleimidopropionate can also been used in immunodiagnostics.
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N-Succinimidyl 3-maleimidopropionate(55750-62-4)Related Product Information
- N-Succinimidyl 6-maleimidohexanoate
- N-Chlorosuccinimide
- Bismaleimide
- Methyl acrylate
- Succinimide
- BUTYL OLEATE
- N-Hydroxysuccinimide
- Tris(trimethylsilyl)phosphate
- O-Phthalimide
- 3-(4-Hydroxyphenyl)propionic acid
- DIALIFOS
- N-Ethylmaleimide
- 3-Maleimidopropionic acid
- N-PROPYLMALEIMIDE
- Maleimide
- 2-OXOCYCLOHEXANECARBONITRILE
- 3-Acryloylamino-1-propanol solution, 50% in water
- MALEIMIDOPROPIONIC ACID N-HYDROXYSULPHOSUCCINIMIDE ESTER