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4-Bromoveratrole

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4-Bromoveratrole Basic information

Product Name:
4-Bromoveratrole
Synonyms:
  • 1-BROMO-3,4-DIMETHOXYBENZENE / 4-BROMOVERATROLE
  • 4-Bromoveratrole,97%
  • 4-Bromoveratrole(4-bromo-1,2-dimethoxybenzene)
  • 4-Bromo-2-methoxyanisole
  • 1,2-Dimethoxy-5-bromobenzene
  • 3,4-Dimethoxy-1-bromobenzene
  • 4-Bromoveratrol
  • Benzene, 4-broMo-1,2-diMethoxy-
CAS:
2859-78-1
MF:
C8H9BrO2
MW:
217.06
EINECS:
220-677-8
Product Categories:
  • Anisole
  • Anisoles, Alkyloxy Compounds & Phenylacetates
  • Aromatic Ethers
  • Bromine Compounds
Mol File:
2859-78-1.mol
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4-Bromoveratrole Chemical Properties

Melting point:
123 °C
Boiling point:
255-256 °C (lit.)
Density 
1.509 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.573(lit.)
Flash point:
229 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Soluble in benzene, ether, toluene.
form 
Liquid
Specific Gravity
1.702
color 
Clear colorless to slightly yellow
BRN 
2046884
InChIKey
KBTMGSMZIKLAHN-UHFFFAOYSA-N
CAS DataBase Reference
2859-78-1(CAS DataBase Reference)
NIST Chemistry Reference
Benzene, 4-bromo-1,2-dimethoxy-(2859-78-1)
EPA Substance Registry System
Benzene, 4-bromo-1,2-dimethoxy- (2859-78-1)
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Safety Information

Hazard Codes 
Xi
Safety Statements 
23-24/25
WGK Germany 
3
TSCA 
T
HS Code 
29093038

MSDS

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4-Bromoveratrole Usage And Synthesis

Chemical Properties

Colorless to Yellow liquid

Uses

4-Bromoveratrole is a metabolite of bromobenzene, with a catechol moiety in the substructure. It also has use as a redox shuttle additive, essentially a component in lithium batteries that consumes excess current during overcharge. It is also used in the synthesis of the isoquinoline alkaloid (-)-mesembrine.

Biological Functions

4-Bromoveratrole has been shown that this molecule binds to the receptor for acetylcholine, which is found in the central nervous system and on muscles. The binding of 4-bromoveratrole to this receptor leads to the release of chloride ions from the cell, which increases the activity of acetylcholine. The detection sensitivity of 4-bromoveratrole in solution was determined by adding malonic acid or hydrochloric acid, which led to an increase in fluorescence intensity. This molecule also has fatty acid and hydroxyl groups that have been shown to have anti-inflammatory properties.

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