BTCP HCL Chemical Properties

Melting point:

80℃ (ethanol )

Boiling point:

425.4±20.0 °C(Predicted)

Density 

1.135±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

H₂O: >180 mg/mL

form 

solid

pka

8.56±0.20(Predicted)

color 

white

Safety Information

RIDADR 

UN 2811 6.1/PG 2

WGK Germany 

3

Toxicity

mouse,LD,intraperitoneal,> 100mg/kg (100mg/kg),United States Patent Document. Vol. #5248686,

BTCP HCL Usage And Synthesis

Uses

Benzothiophenylcyclohexylpiperidine Maleate is a potent dopamine re-uptake/transport inhibitor different from PCP and other stimulants.

Definition

ChEBI: A tertiary amino compound that consists of cyclohexane having piperidin-1-yl and benzothiophen-2-yl groups attached at position 1. A potent dopamine re-uptake inhibitor with a behavioral profile different from that of phencyclidine (PCP) and similar to tha of cocaine.

Biological Activity

A potent dopamine re-uptake inhibitor with a behavioral profile different from that of PCP and similar to that of cocaine.

References

[1] vignon j, pinet v, cerruti c, et al. [3h] n-[1-(2-benzo (b) thiophenyl) cycohexyl] piperidine ([3h] btcp): a new phencyclidine analog selective for the dopamine uptake complex[j]. european journal of pharmacology, 1988, 148(3): 427-436.
[2] chaudieu i, vignon j, chicheportiche m, et al. role of the aromatic group in the inhibition of phencyclidine binding and dopamine uptake by pcp analogs[j]. pharmacology biochemistry and behavior, 1989, 32(3): 699-705.
[3] seeman p. brain dopamine receptors[j]. pharmacological reviews, 1980, 32(3): 229-313.
[4] maurice t, vignon j, kamenka j m, et al. in vivo labelling of the mouse dopamine uptake complex with the phencyclidine derivative [3 h] btcp[j]. neuroscience letters, 1989, 101(2): 234-238.

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