GLUCOPSYCHOSINE CAS#: 52050-17-6

GLUCOPSYCHOSINE Basic information

Product Name:

GLUCOPSYCHOSINE

Synonyms:

sphingosylbeta-glucoside
2-(2-amino-3-hydroxy-octadec-4-enoxy)-6-(hydroxymethyl)oxane-3,4,5-triol
1-β-D-Glucosylsphingosine
(2S,3R,4E)-2-AMino-3-hydroxy-4-octadecenyl β-D-Glucopyranoside
b-D-Glucopyranosyl-1,1’-2’-amino-4’-octadecene-1’,3’-diol Synonym:Glucosylsphingosine
GLUCOSYL(Β) SPHINGOSINE (D18:1)
2-AMino-3-hydroxy-4-octadecenyl β-D-Glucopyranoside
Glucosyl-C18-sphingosine

CAS:

52050-17-6

MF:

C24H47NO7

MW:

461.63

Product Categories:

Amino Acids & Derivatives
Protein Kinase Inhibitors and Activators

Mol File:

52050-17-6.mol

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GLUCOPSYCHOSINE Chemical Properties

Melting point:: >136°C (dec.)
Boiling point:: 664.3±55.0 °C(Predicted)
Density: 1.14±0.1 g/cm3(Predicted)
storage temp.: −20°C
solubility: DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form: Solid
pka: 11.74±0.45(Predicted)
color: White to Off-White
BRN: 4333674
Stability:: Hygroscopic

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Safety Information

Hazard Codes: B
WGK Germany: 3
HS Code: 2932990090

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GLUCOPSYCHOSINE Usage And Synthesis

Chemical Properties

Light Brown Residue

Uses

Glucosyl(β) Sphingosine (d18:1) or D-glucosyl-β1-1′-D-erythro-sphingosine may be used:

to screen lipids that rapidly and reversibly alter?transepithelial?electrical resistance (TER) or tight junction (TJ) permeability in epithelial tissue
as a standard for the quantification of glucosyl sphingosine?in Gaucher patients using liquid chromatography electrospray ionization tandem mass spectrometric (LC/ESI-MS/MS)
as an internal standard for the quantification of lysoglucosylceramide in plasma for Gaucher disease using liquid chromatography with tandem mass spectrometry (LC-MS/MS)

Uses

A sphingosine derivative. A sphingolipid compound found in the the umbilical cord artery of women with preeclampsia.

Definition

ChEBI: Beta-D-glucosylsphingosine is d-Glucosylsphingosine in which the anomeric configuration of the glucosyl moiety is beta. It is a D-glucosylsphingosine and a beta-D-glucoside. It is a conjugate base of a beta-D-glucosylsphingosine(1+).

General Description

Glucosyl?sphingosine is a lyso derivative of glucosylceramide (GlcCer).

Biochem/physiol Actions

Glucosyl?sphingosine is a potential biomarker for Gaucher′s?disease.?It modulates?Ca2+?release?in the brain?microsomes.

GLUCOPSYCHOSINESupplier

J & K SCIENTIFIC LTD.

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Chemsky（shanghai）International Co.,Ltd.

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Shandong Xiya Chemical Co., Ltd

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Hunan Hui Bai Shi Biotechnology Co., Ltd.

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Email: ivy@hnhbsj.com

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 18521732826;
Email: market@aladdin-e.com

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