Basic information Safety Supplier Related

GLUCOPSYCHOSINE

Basic information Safety Supplier Related

GLUCOPSYCHOSINE Basic information

Product Name:
GLUCOPSYCHOSINE
Synonyms:
  • sphingosylbeta-glucoside
  • 2-(2-amino-3-hydroxy-octadec-4-enoxy)-6-(hydroxymethyl)oxane-3,4,5-triol
  • 1-β-D-Glucosylsphingosine
  • (2S,3R,4E)-2-AMino-3-hydroxy-4-octadecenyl β-D-Glucopyranoside
  • b-D-Glucopyranosyl-1,1’-2’-amino-4’-octadecene-1’,3’-diol Synonym:Glucosylsphingosine
  • GLUCOSYL(Β) SPHINGOSINE (D18:1)
  • 2-AMino-3-hydroxy-4-octadecenyl β-D-Glucopyranoside
  • Glucosyl-C18-sphingosine
CAS:
52050-17-6
MF:
C24H47NO7
MW:
461.63
Product Categories:
  • Amino Acids & Derivatives
  • Protein Kinase Inhibitors and Activators
Mol File:
52050-17-6.mol
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GLUCOPSYCHOSINE Chemical Properties

Melting point:
>136°C (dec.)
Boiling point:
664.3±55.0 °C(Predicted)
Density 
1.14±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form 
Solid
pka
11.74±0.45(Predicted)
color 
White to Off-White
BRN 
4333674
Stability:
Hygroscopic
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Safety Information

Hazard Codes 
B
WGK Germany 
3
HS Code 
2932990090
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GLUCOPSYCHOSINE Usage And Synthesis

Chemical Properties

Light Brown Residue

Uses

Glucosyl(β) Sphingosine (d18:1) or D-glucosyl-β1-1′-D-erythro-sphingosine may be used:

  • to screen lipids that rapidly and reversibly alter?transepithelial?electrical resistance (TER) or tight junction (TJ) permeability in epithelial tissue
  • as a standard for the quantification of glucosyl sphingosine?in Gaucher patients using liquid chromatography electrospray ionization tandem mass spectrometric (LC/ESI-MS/MS)
  • as an internal standard for the quantification of lysoglucosylceramide in plasma for Gaucher disease using liquid chromatography with tandem mass spectrometry (LC-MS/MS)

Uses

A sphingosine derivative. A sphingolipid compound found in the the umbilical cord artery of women with preeclampsia.

Definition

ChEBI: Beta-D-glucosylsphingosine is d-Glucosylsphingosine in which the anomeric configuration of the glucosyl moiety is beta. It is a D-glucosylsphingosine and a beta-D-glucoside. It is a conjugate base of a beta-D-glucosylsphingosine(1+).

General Description

Glucosyl?sphingosine is a lyso derivative of glucosylceramide (GlcCer).

Biochem/physiol Actions

Glucosyl?sphingosine is a potential biomarker for Gaucher′s?disease.?It modulates?Ca2+?release?in the brain?microsomes.

GLUCOPSYCHOSINESupplier

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