2-(5-BENZO[1,3]DIOXOL-5-YL-2-TERT-BUTYL-3H-IMIDAZOL-4-YL)-6-METHYLPYRIDINE HYDROCHLORIDE Chemical Properties

storage temp. 

2-8°C

solubility 

DMSO: 24 mg/mL

form 

solid

color 

yellow

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

MSDS

• Language:English Provider:SigmaAldrich

2-(5-BENZO[1,3]DIOXOL-5-YL-2-TERT-BUTYL-3H-IMIDAZOL-4-YL)-6-METHYLPYRIDINE HYDROCHLORIDE Usage And Synthesis

Uses

SB-505124 is a selective inhibitor of transforming growth factor-beta type I receptor ALK5 and as well as being a selective inhibitor of ALK4 but with less potency. SB-505124 blocks TGF-β–induced apoptosis of FaO cells and NRP 154 cells in a concentration-dependent manner. SB-505124 has been shown to suppress the migration and invasion of breast cancer MCF-7-M5 cells.

2-(5-BENZO[1,3]DIOXOL-5-YL-2-TERT-BUTYL-3H-IMIDAZOL-4-YL)-6-METHYLPYRIDINE HYDROCHLORIDE()Related Product Information

• SB216763
• Sb-742457
• MMP-2/MMP-9 INHIBITOR IV
• SB 202190
• SB 743921
• 5-[2-[4-[2-(Dimethylamino)ethoxy]phenyl]-5-(4-pyridinyl)-1H-imidazol-4-yl]-2,3-dihydro-1H-inden-1-one oxime
• 4'-CHLORO-3-METHOXYCINNAMANILIDE
• SB 203580
• SB 225002
• Ispinesib
• SB-505124
• SB 431542
• 6-[2-tert-Butyl-5-(6-methyl-pyridin-2-yl)-1H-imidazol-4-yl]-quinoxaline