O-TERT-BUTYLHYDROXYLAMINE HYDROCHLORIDE Chemical Properties

Melting point:

158-159 °C(lit.)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

H2O: soluble0.5g/10 mL

form 

powder to crystal

color 

White to Almost white

BRN 

3668106

Safety Information

Hazard Codes 

F

Risk Statements 

11

RIDADR 

UN 1325 4.1/PG 3

WGK Germany 

3

F 

10

HazardClass 

4.1

PackingGroup 

Ⅲ

HS Code 

29280090

MSDS

• Language:English Provider:SigmaAldrich

O-TERT-BUTYLHYDROXYLAMINE HYDROCHLORIDE Usage And Synthesis

Chemical Properties

White crystalline powder

Uses

Reactant involved in synthesis of biologically active molecules including:• ;CGS 25966 derivatives for use as MMP inhibitors1• ;Imidazolidinedione derivatives for use as antimalarial treatments2• ;Pyrimidine ribonucleotide analogs as P2Y6 receptor agonists3• ;Rab proteins for isoprenylation and geranylgeranylation inhibition4Reactant involved in:• ;Synthesis of N-(arylethyl)-O-tert-butylhydroxamates for use as Weinreb amide equivalents5• ;Double allylic alkylation of indole-2-hydroxamates6• ;SN2 substitution reactions at amide nitrogens7• ;Photoc

Uses

O-tert-Butylhydroxylamine Hydrochloride is an reactant used in various synthesis of biologically active molecules such as camptothecin derivatives that exerts anti-tumor activity, oxime derivatives as GPR119 agonists and their preparation and highly Potent Matrix Metalloproteinase Inhibitors.

Uses

Reactant involved in synthesis of biologically active molecules including:

• CGS 25966 derivatives for use as MMP inhibitors
• Imidazolidinedione derivatives for use as antimalarial treatments
• Pyrimidine ribonucleotide analogs as P2Y6 receptor agonists
• Rab proteins for isoprenylation and geranylgeranylation inhibition

• Synthesis of N-(arylethyl)-O-tert-butylhydroxamates for use as Weinreb amide equivalents
• Double allylic alkylation of indole-2-hydroxamates
• SN2 substitution reactions at amide nitrogens
• Photocycloaddition to C=N bonds for synthesis of 1,3-diazepines

O-TERT-BUTYLHYDROXYLAMINE HYDROCHLORIDE(39684-28-1)Related Product Information

• Dimethylamine hydrochloride
• HYDROXYLAMINE
• O-Benzoyl-N-tert-butylhydroxylamine Hydrochloride
• O-Acetyl-N-tert-butylhydroxylamine Hydrochloride
• Cefmepidium chloride
• 3-(2-CHLORO-PHENYL)-5-METHYL-4,5-DIHYDRO-ISOXAZOLE-5-CARBOXYLIC ACID
• O-TERT-BUTYLHYDROXYLAMINE HYDROCHLORIDE
• 1-Carboxy-1-methylethoxyammonium chloride
• 1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride monohydrochloride