[Hydroxy(tosyloxy)iodo]benzene
[Hydroxy(tosyloxy)iodo]benzene Basic information
- Product Name:
- [Hydroxy(tosyloxy)iodo]benzene
- Synonyms:
-
- Iodine,hydroxy(4-Methylbenzenesulfonato-kO)phenyl-
- [Hydroxy(tosyloxy)iodo]benzene 96%
- [Hydroxy(4-toluenesulfonato)iodo]benzene
- Hydroxy(phenyl)iodo tosylate
- [Hydroxy(tosyloxy)iodo]benzene≥ 98%(Titration)
- Hydroxy{[(4-methylphenyl)sulfonyl]oxy} phenyliodine
- Koser's Regent ,HTIB
- Hydroxyl(toluenesulfonyloxygengeneration)iodobenzene
- CAS:
- 27126-76-7
- MF:
- C13H13IO4S
- MW:
- 392.21
- EINECS:
- 629-501-8
- Product Categories:
-
- Hypervalent Iodine Compounds
- Oxidation
- Synthetic Organic Chemistry
- Phenyls & Phenyl-Het
- Mol File:
- 27126-76-7.mol
More
Less
[Hydroxy(tosyloxy)iodo]benzene Chemical Properties
- Melting point:
- 131-137 °C (lit.)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- soluble in Methanol
- form
- Crystalline Powder
- pka
- 7.59±0.58(Predicted)
- color
- Pale yellow
- Sensitive
- Light Sensitive
- Merck
- 14,5321
- BRN
- 2150074
- InChIKey
- LRIUKPUCKCECPT-UHFFFAOYSA-N
- CAS DataBase Reference
- 27126-76-7(CAS DataBase Reference)
More
Less
MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
More
Less
[Hydroxy(tosyloxy)iodo]benzene Usage And Synthesis
Chemical Properties
Pale yellow crystalline powder
Uses
Reactant for:
- Ligand-free palladium-catalyzed Heck-type coupling reactions
- Preparation of carbodiimides via dehydrosulfurization of thioureas
- Preparation of nitriles by oxidative conversion of alcohols, aldehydes, and amines
- Preparation of substituted anilines via aromatic aldoxime reaction
- Preparation of tetrahydrofurans by oxidative cyclization of homoallylic alcohols
- Preparation of isoxazoline N-Oxides from ?-hydroxyketoximes via oxidative N-O coupling
- Ring expansion in synthesis of aminopeptidase inhibitors
- Oxidation and protonation reactions in acidic conditions
Uses
Versatile synthetic reagent in phenyliodination and/or tosylation of a range of organic substrates; in oxidative transformations including oxidative rearrangements.
Purification Methods
Possible impurities are tosic acid (removed by washing with Me2CO) and acetic acid (removed by washing with Et2O). It is purified by dissolving in the minimum volume of MeOH, adding Et2O to cloud point and setting aside for the prisms to separate [Koser & Wettach J Org Chem 42 1476 1977, NMR: Koser et al. J Org Chem 41 3609 1976]. It has also been crystallised from CH2Cl2 (needles, m 140-142o) [Neiland & Karele J Org Chem, USSR (Engl Transl) 6 889 1970].
[Hydroxy(tosyloxy)iodo]benzeneSupplier
Shanghai Yurlic Chemical S&T Co.Ltd. Gold
- Tel
- 021-37285141 15618858630
- yancf@yulibiotech.com
SiChuang NanBu Honesty Technology Co., Ltd.
- Tel
- 0838-5675166 15883665058
- nbcxkj@126.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel
- 021-61259108 18621169109
- market03@meryer.com
future industrial shanghai co., ltd
- Tel
- 400-0066400 13621662912
- sales@jonln.com
More
Less
[Hydroxy(tosyloxy)iodo]benzene(27126-76-7)Related Product Information
- Butylated Hydroxytoluene
- Benzene
- Ethylbenzene
- Tosyl chloride
- Tosyl cyanide
- Allylbenzene
- p-Toluenesulfonamide
- Fipronil
- CHLOROPHOSPHONAZO III
- TOLBUTAMIDE
- Iodosobenzene
- 2-(4-Aminopentyl(ethyl)amino)ethanol
- HYDROXY ITRACONAZOLE
- Hydroxyacetic Acid Hydrazide
- Iodobenzene
- [Hydroxy(tosyloxy)iodo]benzene
- [HYDROXY(METHANESULFONYLOXY)IODO]BENZENE
- 1-[[(4-METHYLPHENYL)SULPHONYL]OXY]-1,2-BENZIODOXOL-3(1H)-ONE