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[Hydroxy(tosyloxy)iodo]benzene

Product Name
[Hydroxy(tosyloxy)iodo]benzene
CAS No.
27126-76-7
Chemical Name
[Hydroxy(tosyloxy)iodo]benzene
Synonyms
HTIB;HYDROXY(TOSYLOXY)IODOBENZENE;Koser Reagent;[hydroxy(phenyl)-λ3-iodanyl] 4-methylbenzenesulfonate;NSC 294176;AKOS 91494;Koser's Regent;[Hydroxy(tosyL;KOSER'S REAGENT;oxy)iodo]benzene
CBNumber
CB6778895
Molecular Formula
C13H13IO4S
Formula Weight
392.21
MOL File
27126-76-7.mol
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[Hydroxy(tosyloxy)iodo]benzene Property

Melting point:
131-137 °C (lit.)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
soluble in Methanol
form 
Crystalline Powder
pka
7.59±0.58(Predicted)
color 
Pale yellow
Sensitive 
Light Sensitive
Merck 
14,5321
BRN 
2150074
InChIKey
LRIUKPUCKCECPT-UHFFFAOYSA-N
CAS DataBase Reference
27126-76-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/38
Safety Statements 
26-36
WGK Germany 
3
8
HazardClass 
IRRITANT
HS Code 
29039990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
301035
Product name
[Hydroxy(tosyloxy)iodo]benzene
Purity
96%
Packaging
5g
Price
$33.84
Updated
2024/03/01
Sigma-Aldrich
Product number
301035
Product name
[Hydroxy(tosyloxy)iodo]benzene
Purity
96%
Packaging
25g
Price
$162
Updated
2024/03/01
TCI Chemical
Product number
P1015
Product name
[Hydroxy(tosyloxy)iodo]benzene
Purity
>97.0%(T)
Packaging
5g
Price
$92
Updated
2024/03/01
TCI Chemical
Product number
P1015
Product name
[Hydroxy(tosyloxy)iodo]benzene
Purity
>97.0%(T)
Packaging
25g
Price
$375
Updated
2024/03/01
Alfa Aesar
Product number
L15701
Product name
Hydroxy(tosyloxy)iodobenzene, 97%
Packaging
5g
Price
$37.65
Updated
2024/03/01
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[Hydroxy(tosyloxy)iodo]benzene Chemical Properties,Usage,Production

Chemical Properties

Pale yellow crystalline powder

Uses

Reactant for:

  • Ligand-free palladium-catalyzed Heck-type coupling reactions
  • Preparation of carbodiimides via dehydrosulfurization of thioureas
  • Preparation of nitriles by oxidative conversion of alcohols, aldehydes, and amines
  • Preparation of substituted anilines via aromatic aldoxime reaction
  • Preparation of tetrahydrofurans by oxidative cyclization of homoallylic alcohols
  • Preparation of isoxazoline N-Oxides from ?-hydroxyketoximes via oxidative N-O coupling
  • Ring expansion in synthesis of aminopeptidase inhibitors
  • Oxidation and protonation reactions in acidic conditions

Uses

Versatile synthetic reagent in phenyliodination and/or tosylation of a range of organic substrates; in oxidative transformations including oxidative rearrangements.

Purification Methods

Possible impurities are tosic acid (removed by washing with Me2CO) and acetic acid (removed by washing with Et2O). It is purified by dissolving in the minimum volume of MeOH, adding Et2O to cloud point and setting aside for the prisms to separate [Koser & Wettach J Org Chem 42 1476 1977, NMR: Koser et al. J Org Chem 41 3609 1976]. It has also been crystallised from CH2Cl2 (needles, m 140-142o) [Neiland & Karele J Org Chem, USSR (Engl Transl) 6 889 1970].

[Hydroxy(tosyloxy)iodo]benzene Preparation Products And Raw materials

Raw materials

Preparation Products

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[Hydroxy(tosyloxy)iodo]benzene Suppliers

Shanghai Yurlic Chemical S&T Co.Ltd.
Tel
021-37285141 15618858630
Fax
021-37285142
Email
yancf@yulibiotech.com
Country
China
ProdList
170
Advantage
58
Innochem(Beijing) Technology Co.,Ltd.
Tel
10-56541685 13070143590
Fax
010-56541685
Email
sales@innochem.cn
Country
China
ProdList
98
Advantage
57
SiChuang NanBu Honesty Technology Co., Ltd.
Tel
0838-5675166 15883665058
Fax
0838-5675535
Email
nbcxkj@126.com
Country
China
ProdList
668
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1998
Advantage
65
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6013
Advantage
61
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
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View Lastest Price from [Hydroxy(tosyloxy)iodo]benzene manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
[Hydroxy(tosyloxy)iodo]benzene 27126-76-7
Price
US $30.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2000kg
Release date
2024-03-22
WUHAN FORTUNA CHEMICAL CO., LTD
Product
[Hydroxy(tosyloxy)iodo]benzene 27126-76-7
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-01-16
Zhuozhou Wenxi import and Export Co., Ltd
Product
Hydroxy(tosyloxy)iodobenzene 27126-76-7
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

27126-76-7, [Hydroxy(tosyloxy)iodo]benzeneRelated Search:


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