[Hydroxy(tosyloxy)iodo]benzene
- Product Name
- [Hydroxy(tosyloxy)iodo]benzene
- CAS No.
- 27126-76-7
- Chemical Name
- [Hydroxy(tosyloxy)iodo]benzene
- Synonyms
- HTIB;HYDROXY(TOSYLOXY)IODOBENZENE;Koser Reagent;[hydroxy(phenyl)-λ3-iodanyl] 4-methylbenzenesulfonate;NSC 294176;AKOS 91494;Koser's Regent;[Hydroxy(tosyL;KOSER'S REAGENT;KOSER'S REAGENT
- CBNumber
- CB6778895
- Molecular Formula
- C13H13IO4S
- Formula Weight
- 392.21
- MOL File
- 27126-76-7.mol
[Hydroxy(tosyloxy)iodo]benzene Property
- Melting point:
- 131-137 °C (lit.)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- soluble in Methanol
- form
- Crystalline Powder
- pka
- 7.59±0.58(Predicted)
- color
- Pale yellow
- Sensitive
- Light Sensitive
- Merck
- 14,5321
- BRN
- 2150074
- InChIKey
- LRIUKPUCKCECPT-UHFFFAOYSA-N
- CAS DataBase Reference
- 27126-76-7(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 301035
- Product name
- [Hydroxy(tosyloxy)iodo]benzene
- Purity
- 96%
- Packaging
- 5g
- Price
- $33.84
- Updated
- 2024/03/01
- Product number
- 301035
- Product name
- [Hydroxy(tosyloxy)iodo]benzene
- Purity
- 96%
- Packaging
- 25g
- Price
- $162
- Updated
- 2024/03/01
- Product number
- P1015
- Product name
- [Hydroxy(tosyloxy)iodo]benzene
- Purity
- >97.0%(T)
- Packaging
- 5g
- Price
- $92
- Updated
- 2024/03/01
- Product number
- P1015
- Product name
- [Hydroxy(tosyloxy)iodo]benzene
- Purity
- >97.0%(T)
- Packaging
- 25g
- Price
- $375
- Updated
- 2024/03/01
- Product number
- L15701
- Product name
- Hydroxy(tosyloxy)iodobenzene, 97%
- Packaging
- 5g
- Price
- $37.65
- Updated
- 2024/03/01
[Hydroxy(tosyloxy)iodo]benzene Chemical Properties,Usage,Production
Chemical Properties
Pale yellow crystalline powder
Uses
Reactant for:
- Ligand-free palladium-catalyzed Heck-type coupling reactions
- Preparation of carbodiimides via dehydrosulfurization of thioureas
- Preparation of nitriles by oxidative conversion of alcohols, aldehydes, and amines
- Preparation of substituted anilines via aromatic aldoxime reaction
- Preparation of tetrahydrofurans by oxidative cyclization of homoallylic alcohols
- Preparation of isoxazoline N-Oxides from ?-hydroxyketoximes via oxidative N-O coupling
- Ring expansion in synthesis of aminopeptidase inhibitors
- Oxidation and protonation reactions in acidic conditions
Uses
Versatile synthetic reagent in phenyliodination and/or tosylation of a range of organic substrates; in oxidative transformations including oxidative rearrangements.
Purification Methods
Possible impurities are tosic acid (removed by washing with Me2CO) and acetic acid (removed by washing with Et2O). It is purified by dissolving in the minimum volume of MeOH, adding Et2O to cloud point and setting aside for the prisms to separate [Koser & Wettach J Org Chem 42 1476 1977, NMR: Koser et al. J Org Chem 41 3609 1976]. It has also been crystallised from CH2Cl2 (needles, m 140-142o) [Neiland & Karele J Org Chem, USSR (Engl Transl) 6 889 1970].
[Hydroxy(tosyloxy)iodo]benzene Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from [Hydroxy(tosyloxy)iodo]benzene manufacturers
- Product
- [Hydroxy(tosyloxy)iodo]benzene 27126-76-7
- Price
- US $30.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 2000kg
- Release date
- 2024-05-14
- Product
- [Hydroxy(tosyloxy)iodo]benzene 27126-76-7
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-01-16
- Product
- Hydroxy(tosyloxy)iodobenzene 27126-76-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27