Basic information Safety Supplier Related

(+/-)-VESAMICOL HYDROCHLORIDE

Basic information Safety Supplier Related

(+/-)-VESAMICOL HYDROCHLORIDE Basic information

Product Name:
(+/-)-VESAMICOL HYDROCHLORIDE
Synonyms:
  • (+/-)-TRANS-2-(4-PHENYLPIPERIDINYL)CYCLOHEXANOL HYDROCHLORIDE
  • (+/-)-VESAMICOL HYDROCHLORIDE
  • AH5183 HCL
  • 2-(4-Phenyl-1-piperidinyl)cyclohexanol
  • 2-(4-Phenylpiperidino)cyclohexanol
  • 23965-53-9 (Hydrochloride)
  • Cyclohexanol, 2-(4-phenyl-1-piperidinyl)-
CAS:
22232-64-0
MF:
C17H25NO
MW:
259.39
Mol File:
22232-64-0.mol
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(+/-)-VESAMICOL HYDROCHLORIDE Chemical Properties

storage temp. 
Store at RT
form 
Solid
color 
White to off-white
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(+/-)-VESAMICOL HYDROCHLORIDE Usage And Synthesis

Uses

Vesamicol is a compound used to synthesize radiolabeled derivatives that can be used as sigma receptor ligands for tumor targeting inhibition and have shown certain potential in cellular uptake, biodistribution and inhibition experiments.

Definition

ChEBI: 2-(4-phenyl-1-piperidinyl)-1-cyclohexanol is a member of piperidines.

Biological Activity

Inhibitor of acetylcholine transport (K i = 2 nM). Centrally active following systemic administration in vivo .

References

[1] Astatine-211-labeled aza-vesamicol derivatives as sigma receptor ligands for targeted alpha therapy DOI:10.1016/j.nucmedbio.2023.108369

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