Astegolimab Chemical Properties

form 

Liquid

color 

Colorless to light yellow

Astegolimab Usage And Synthesis

Uses

Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody that blocks IL-33 signaling by targeting ST2, the IL-33 receptor. Astegolimab has the potential for chronic obstructive pulmonary disease (COPD) research[1].

IC 50

ST2

References

[1] Steven G Kelsen, et al. Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: A randomized clinical trial. J Allergy Clin Immunol. 2021 Sep;148(3):790-798. DOI:10.1016/j.jaci.2021.03.044

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